| 靖婧,苗延巍.优化低剂量一站式全脑CT灌注成像联合CTA扫描方案[J].中国医学影像技术,2018,34(3):424~428 |
| 优化低剂量一站式全脑CT灌注成像联合CTA扫描方案 |
| Optimization of scanning protocol in low-dose one-stop CT perfusion imaging combined with CTA of whole brain |
| 投稿时间：2017-06-13 修订日期：2017-12-26 |
| DOI：10.13929/j.1003-3289.201706077 |
| 中文关键词: 体层摄影术,X线计算机 脑 灌注成像 血管造影术 |
| 英文关键词:Tomography,X-ray computed Brain Perfusion imaging Angiography |
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| 中文摘要: |
| 目的 探讨优化一站式全脑CT灌注成像（CTP）联合CTA扫描方案。方法 对45例受检者行一站式全脑CTP联合CTA，共进行22期相扫描，并采用3种扫描方案，选取第10期相灌注图像重建CTA图像，其中A组为自动管电流调制（ATCM）技术及低噪声指数（噪声指数=2），B组为管电流325 mA，C组为ATCM及稍低噪声指数（噪声指数=2.5）；3组其余各期相均采用ATCM技术且噪声指数设定为8；3组扫描方案的管电压均为100 kV。记录辐射剂量相关参数，比较CTA、CTP图像的噪声（SD）、SNR、CNR及不同部位脑实质各灌注参数值及CTA、CTP图像的主观评分。结果 3组有效剂量（ED）差异有统计学意义（P<0.05），其中A组ED明显高于B、C组（P=0.043、0.001）；3组CTA图像噪声、SNR、CNR及主观评分差异无统计学意义（P=0.218、0.545、0.575、0.900），CTP图像相应部位图像噪声、SNR、各灌注参数值及主观评分差异均无统计学意义（P均>0.05）。结论 采用ATCM技术一站式全脑CTP联合CTA检查可通过适当增加噪声指数减低患者辐射剂量。 |
| 英文摘要: |
| Objective To optimize protocol in one-stop whole brain CT perfusion imaging (CTP) combined with CTA. Methods Totally 45 subjects underwent one-stop whole brain CTP combined with CTA with three different scanning protocols and 22 phases. CTA images were reconstructed from CTP original data at the tenth phase, the protocols of three scanning groups were as follows:Group A using automatic tube current modulation technique (ATCM) with low noise index (NI; NI=2), group B with fixed tube current (325 mA) and group C using ATCM with slightly low NI (NI=2.5), and the other phases of three groups were performed with ATCM and NI=8. Tube voltage of all three scanning protocols was 100 kV. The radiation dose and related parameters were recorded. Objective parameters including image noise (SD), SNR, CNR and perfusion parameters in different parts of the brain parenchyma and subjective scores of CTA, CTP image quality were compared among three groups. Results There was significant difference of effective dose (ED) among three groups (P<0.05). ED of group A was higher than that of group B and C (P=0.043, 0.001). No difference was found in CTA image noise, SNR, CNR nor subjective scores among three groups (P=0.218, 0.545, 0.575, 0.900), neither of CTP images among three groups (P>0.05). Conclusion Using ATCM and increasing NI appropriately may reduce radiation dose in one-stop CTP combined with CTA. |
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