| 张建发,陈秀君,李雯靖,黄钟杰,钟朝森,周光照,林顺发.离体生物软组织同步辐射相衬CT成像[J].中国医学影像技术,2018,34(2):171~175 |
| 离体生物软组织同步辐射相衬CT成像 |
| Synchrotron radiation phase contrast CT imaging of in vitro biological soft tissue |
| 投稿时间：2017-07-14 修订日期：2017-11-29 |
| DOI：10.13929/j.1003-3289.201707062 |
| 中文关键词: 同步辐射 体层摄影术,X线计算机 软组织 |
| 英文关键词:Synchrotron radiation Tomography, X-ray computed Soft tissue |
| 基金项目:2015年度汕头市医疗科技计划项目（汕府科[2015]123号）。 |
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| 中文摘要: |
| 目的 探讨同步辐射相衬CT对离体生物软组织成像的可行性。方法 将手术切除人贲门标本3块、食管及食管癌标本各2块及自尸体标本提取的大脑中动脉组织2块固定并自然干燥，之后行同步辐射相衬CT成像，观察成像显示的软组织结构，并与病理结果进行对照。结果 同步辐射相衬CT图像清晰显示正常贲门及食管壁3层结构，即黏膜层、黏膜下层及肌层，黏膜面光整；在食管癌标本则显示癌组织浸润食管壁；对大脑中动脉组织可清晰显示脑动脉管壁及血管腔内状况。结论 同步辐射相衬CT成像能清晰显示离体生物软组织的细微结构。 |
| 英文摘要: |
| Objective To explore the feasibility of in vitro biological soft tissue imaging by using synchrotron radiation phase contrast CT. Methods Three samples of resected human cardia, two samples of resected human esophageal carcinoma and esophagus, as well as two samples of middle cerebral artery tissue extracted from corpses were fixed and air-dried at room temperature for synchrotron radiation phase contrast CT imaging. The images of soft tissue structures were observed and compared with pathological findings. Results The images of synchrotron radiation phase contrast CT showed three-layer structure of cardia and esophagus, mucous, submucosa and muscular layer. The surface of mucous layer was smooth. The images of esophageal carcinoma showed cancerous tissue infiltrating esophageal wall. The wall and lumen of cerebral arteries could be also clearly displayed. Conclusion Synchrotron radiation phase contrast CT imaging can clearly display fine structures of in vitro biological soft tissue. |
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