贺方方,丁利军,朱颖春,周建军.子宫内膜区域不均质回声对体外受精/卵胞浆内单精子显微注射临床结局的影响[J].中国医学影像技术,2018,34(1):90~93
子宫内膜区域不均质回声对体外受精/卵胞浆内单精子显微注射临床结局的影响
Impact of heterogeneous echo in endometrial region on clinical outcome of fertilization in vitro/intracytoplasmic sperm injection
投稿时间:2017-03-14  修订日期:2017-10-30
DOI:10.13929/j.1003-3289.201703066
中文关键词:  受精,体外  子宫内膜  妊娠  超声检查
英文关键词:Fertilization in vitro  Endometrium  Pregnancy  Ultrasonography
基金项目:国家自然科学基金(81571391)。
作者单位E-mail
贺方方 南京鼓楼医院 南京大学医学院附属南京鼓楼医院生殖医学中心, 江苏 南京 210008  
丁利军 南京鼓楼医院 南京大学医学院附属南京鼓楼医院生殖医学中心, 江苏 南京 210008  
朱颖春 南京鼓楼医院 南京大学医学院附属南京鼓楼医院生殖医学中心, 江苏 南京 210008  
周建军 南京鼓楼医院 南京大学医学院附属南京鼓楼医院生殖医学中心, 江苏 南京 210008 zhou6jj@sina.com 
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中文摘要:
      目的 评估体外受精/卵胞浆内单精子显微注射(IVF/ICSI)治疗过程中子宫内膜区域不均质回声对妊娠概率的影响。方法 收集接受IVF/ICSI治疗患者334例,根据IVF/ICSI促排卵过程中B超结果,分为不均质回声组(n=88)和正常回声组(n=246),比较两组患者妊娠情况。结果 正常回声组妊娠概率高于不均质回声组[78.86%(194/246) vs 68.18%(60/88),P=0.01],正常回声组异位妊娠率低于不均质回声组[1.03%(2/194) vs 5.00%(3/60),P=0.01]。不均质回声组和正常回声组内膜增厚患者妊娠率高于无增厚患者(P均<0.05)。结论 不孕症患者合并内膜区域不均质回声时,妊娠成功率明显降低,异位妊娠率明显增高;但子宫内膜厚度大于10 mm依然有利于妊娠。
英文摘要:
      Objective To observe the impact of heterogeneous echo in endometrial region on pregnancy rate after fertilization in vitro/intracytoplasmic sperm injection (IVF/ICSI).Methods Totally 334 patients who underwent IVF/ICSI therapy were enrolled.According to results of B-mode ultrasound in the course of promoting drainage,the patients were divided into heterogeneous echo group (n=88) and normal echo group (n=246).Pregnancy conditions were compared between the two groups.Results Heterogeneous echo group showed significant lower pregnant rate than normal echo group (68.18%[60/88]vs 78.86%[194/246],P=0.01),while the ectopic pregnancy rate of heterogeneous echo group was higher than that of the normal echo group (5.00%[3/60]vs 1.03%[2/194],P=0.01).Pregnancy rate of endometrial thickness patients were higher than that of patients without endometrial thickness in two groups (all P<0.05).Conclusion Pregnant rate reduced and ectopic pregnancy rate increased in infertility patients with endometrial heterogeneous echo,while higher 10 mm endometrial thickness could contribute to increase pregnant rate.
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