| 曾欣,邓旦,梁诗敏,刘先梅,李茜.超声斑点追踪技术评估兔胸部爆震伤后急性期左心功能[J].中国医学影像技术,2018,34(1):10~14 |
| 超声斑点追踪技术评估兔胸部爆震伤后急性期左心功能 |
| Ultrasound speckle tracking imaging in evaluation on left ventricular function in acute stage chest blast injury of rabbits |
| 投稿时间：2017-04-10 修订日期：2017-09-11 |
| DOI：10.13929/j.1003-3289.201704041 |
| 中文关键词: 斑点追踪技术 胸部 心室功能,左 兔 创伤和损伤 |
| 英文关键词:Speckle tracking imaging Chest Ventricular function,left Rabbits Wounds and injuries |
| 基金项目: |
|
| 摘要点击次数: 2659 |
| 全文下载次数: 982 |
| 中文摘要: |
| 目的 采用超声斑点追踪技术（STI）分析胸部爆震对左心室功能和心肌应变的影响。方法 将50只雌雄不限的健康新西兰兔随机分成4组，其中未爆震实验兔作为正常组（n=5），将剩余实验兔置于特定的半封闭爆破环境中，用瞬发电雷管按照不同的距离爆炸，制作轻、中及重度胸部爆震伤的动物模型，标记为A、B、C组（每组15只）。对各组实验兔采用常规超声心动图及超声斑点追踪技术检测左心室功能变化，采用二维应变分析软件测量左心室各节段的纵向应变（LS），并进行统计学分析。结果 A组实验兔爆震伤后左心室射血分数（EF）、左心室短轴缩短率（FS）与正常组差异无统计学意义（P均>0.05），其左心室前壁、前间隔及侧壁LS较正常组减低（P均<0.05）；B、C组左心室EF、FS及各节段LS均低于正常组相应指标（P均<0.05）。C组EF、FS及各节段LS均低于A组（P均<0.05）；B、C组比较EF、FS无明显差异，但C组基底段和中间段的前壁、侧壁及心尖段的侧壁LS低于B组（P均<0.05）。结论 胸部爆震伤后超声斑点追踪技术可更早、更敏感地反映实验兔心脏各节段功能的变化情况。 |
| 英文摘要: |
| Objective To evaluate the impact of chest blast injury on left ventricular function and myocardial strain with speckle tracking imaging (STI).Methods Fifty healthy New Zealand rabbits were randomly divided into 4 groups. Five rabbits without blast injury were used as a normal group, and the other rabbits were placed in specific semi-enclosed blasting environment in accordance with the different distance of the explosion. With instantaneous detonators, slight, medium and heavy chest blast injury animal models were produced and labeled as A, B, and C group (each n=15), respectively. The left ventricular function was measured with conventional echocardiography and STI. The longitudinal strain (LS) of the left ventricle was measured with two-dimensional strain analysis software and statistically analyzed.Results There was no significant difference of ejection fraction (EF) and fractional shortening (FS) in the left ventricle after chest blast injury between group A and normal group (all P>0.05), while LS of anterior wall, anterior septum wall and lateral wall of group A significantly decreased compared with those of normal group (all P<0.05). In group B and C, the left ventricular EF, FS and LS of each segment were lower than those of normal group (all P<0.05). In group C, the left ventricular EF, FS and LS of each segment were lower than those in group A (all P<0.05). There was no significant difference of EF and FS between group B and group C. In group C, LS of anterior wall and lateral wall of basal segment and middle segment were lower than those of group B (all P<0.05).Conclusion STI can reflect functional changes of left ventricle in each segment earlier and more sensitively after chest blast injury. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
