| 江建芹,崔磊,顾晓雯,蔡荣芳.体素内不相干运动模型扩散加权成像在肿瘤疗效评估中的进展[J].中国医学影像技术,2017,33(6):949~953 |
| 体素内不相干运动模型扩散加权成像在肿瘤疗效评估中的进展 |
| Progresses of intravoxel incoherent motion DWI in evaluation of treatment response of tumors |
| 投稿时间：2016-11-23 修订日期：2017-03-27 |
| DOI：10.13929/j.1003-3289.201611120 |
| 中文关键词: 磁共振成像 体素内不相干运动 肿瘤 |
| 英文关键词:Magnetic resonance imaging Intravoxel incoherent motion Neoplasms |
| 基金项目: |
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| 中文摘要: |
| DWI的体素内不相干运动（IVIM）模型可区分水分子的真性扩散与微循环灌注形成的假性扩散，获得纯扩散系数（D）、伪扩散系数（D*）和灌注分数（f），能有效检出肿瘤治疗后细胞活性及微循环灌注的变化，可早期评价肿瘤疗效、优化治疗方案及预测预后，为临床选择合适的治疗方案提供依据。本文对IVIM在肿瘤疗效评估中的应用和研究进展进行综述。 |
| 英文摘要: |
| Intravoxel incoherent motion (IVIM) can distinguish the molecular diffusion from the pseudo-diffusion of microcircular perfusion to obtain true diffusion coefficient (D), pseudo-diffusion coefficient (D*) and perfusion fraction (f), which are sensitive to detect alterations in cellularity and microcirculation perfusion. IVIM can also evaluate early therapeutic effects, optimize treatment plan, predict prognoses, and provide information for choosing appropriate treatment methods. In this paper, the principle of IVIM and its application in tumor response evaluation were reviewed. |
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