| 葛玉林.多发性硬化的影像学研究:血流动力学和氧代谢变化[J].中国医学影像技术,2017,33(6):805~809 |
| 多发性硬化的影像学研究:血流动力学和氧代谢变化 |
| Imaging studies of multiple sclerosis: Hemodynamics and changes in oxygen metabolism |
| 投稿时间：2016-12-05 修订日期：2017-04-05 |
| DOI：10.13929/j.1003-3289.201612010 |
| 中文关键词: 多发性硬化 磁共振成像 炎症 线粒体 |
| 英文关键词:Multiple sclerosis Magnetic resonance imaging Inflammation Mitochondria |
| 基金项目: |
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| 中文摘要: |
| 多发性硬化（MS）患者早期存在神经炎性改变和广泛神经变性，两者间的关系还有待研究。最近的神经影像学研究显示，由于有效氧代谢和氧供应缺陷导致的能量衰竭可能是神经变性的原因之一。本文对能量代谢障碍的病理机制和相关MRI影像学技术的应用进行综述。 |
| 英文摘要: |
| The relationship between neuronal inflammatory changes and extensive neurodegeneration in patients with multiple sclerosis (MS) remains to be studied. Recent neuroimaging studies have shown that energy depletion due to the impairment of effective oxygen metabolism and oxygen supply defects may be one of the causes of neurodegeneration. In this paper, the pathologic mechanism of MS related to energy failure and associated MRI imaging techniques were reviewed. |
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