| 李振洲,任力杰,邵玉凤,陈胜华,秦豫,关晓韵,吴欣殷.CEUS颈动脉斑块灌注模式与短暂性脑缺血发作患者脑卒中发病的关系[J].中国医学影像技术,2017,33(4):534~538 |
| CEUS颈动脉斑块灌注模式与短暂性脑缺血发作患者脑卒中发病的关系 |
| Relationship between perfusion mode of carotid plaque in CEUS and ischemic stroke in transient ischemic attack patients |
| 投稿时间：2016-10-01 修订日期：2017-02-15 |
| DOI：10.13929/j.1003-3289.201610002 |
| 中文关键词: 颈动脉 斑块 脑缺血发作,短暂性 造影剂 超声检查 |
| 英文关键词:Carotid arteries Plaque Ischemic attack, transient Contrast media Ultrasonography |
| 基金项目:深圳市科技计划项目（JCYJ20140414170821323）。 |
|
| 摘要点击次数: 3337 |
| 全文下载次数: 853 |
| 中文摘要: |
| 目的 探讨短暂性脑缺血发作（TIA）患者颈动脉斑块CEUS的增强模式及与发生缺血性脑卒中及再发TIA的相关性。方法 对符合纳入标准的73例患者行颈动脉常规超声检查，选择颈总动脉分叉处及颈内动脉起始段斑块厚度>2.5 mm的61例患者进行CEUS检查，随访至少18个月，并将患者分为再发病组与未再发病组。患者18个月内发生缺血性脑卒中或再发TIA的危险因素采用Logistic回归分析。结果 两组高血压、糖尿病、高血脂、吸烟史、脑卒中家族史、服药依从性、二维超声及CEUS特征差异均有统计学意义（P均<0.05）。多变量Logistic回归分析显示，影响再发病的因素按强度大小排列，分别为CEUS特征、高血压、药物依从性、高血糖及二维超声特征。结论 CEUS可对颈动脉斑块内新生血管的灌注模式进行评估，并对TIA患者发生缺血性脑卒中或再发TIA进行预测，对指导临床进行针对性预防有重要价值。 |
| 英文摘要: |
| Objective To evaluate the relationship between the perfusion mode of neovascularization of carotid plaque in CEUS and the ischemic stroke in transient ischemic attack (TIA) patient. Methods A total of 73 TIA patients according to the inclusive criteria were enrolled. All the patients underwent routine carotid ultrasonic examination. And 61 patients with plaque thicker than 2.5 mm in carotid bifurcation underwent CEUS and follow-up for at least 18 months. All the patients were divided into recurrent and non-recurrent groups. Logistic regression analysis were performed to detect the risk factors for incurrence of ischemic stroke or recurrence of TIA in 18 months. Results There were statistical differences between 2 groups in hypertension, diabetes, hyperlipemia, smoking history, family history of stroke, medication compliance, two-dimensional ultrasound and CEUS characteristics (all P<0.05). Multivariate Logistic regression analysis showed that all the factors correlated with the recurrency, from big to small order were the CEUS characteristics of carotid plaque, hypertension, medication compliance, diabetes, two-dimensional ultrasound characteristics of carotid plaque. Conclusion CEUS could evaluate the perfusion mode of neovascularization in carotid plaques. For TIA patients, CEUS could predict the incurrence of ischemic stroke or recurrence of TIA, which can guide TIA patients targeted prophylaxis of them. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
