| 王婧玲,吴锐,张卫平,陈莉.唾液腺超声评分法诊断干燥综合征的价值[J].中国医学影像技术,2017,33(3):394~398 |
| 唾液腺超声评分法诊断干燥综合征的价值 |
| Diagnostic value of salivary gland ultrasonography scoring systems in Sjögren's syndrome |
| 投稿时间：2016-08-16 修订日期：2016-12-24 |
| DOI：10.13929/j.1003-3289.201608067 |
| 中文关键词: 干燥综合征 超声检查 唾液腺 |
| 英文关键词:Sjögren's syndrome Ultrasonography Salivary glands |
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| 中文摘要: |
| 目的 探讨唾液腺超声评分法对干燥综合征（SS）的诊断价值。方法 收集我院风湿免疫科门诊或住院的口干、眼干患者92例，将患者分为SS组42例和非SS组50例。对所有患者双侧腮腺及颌下腺进行二维超声检查，获得双侧腮腺及颌下腺的声像图，采用半定量评分方法对其进行评分。比较两组唾液腺超声评分的差异并分析其诊断SS的价值。结果 非SS组中38例（38/50，76.00%）唾液腺超声表现正常，评为0分，SS组32例（32/42，76.19%）唾液腺超声评分≥1分。SS组唾液腺超声评分高于非SS组（P<0.001）。唾液腺超声评分诊断SS的ROC曲线下面积为0.805[P<0.001，95%可信区间（0.711，0.899）]，以2分为临界值诊断SS敏感度为59.5%，特异度为92.0%。结论 唾液腺超声评分法可为唾液腺回声的均匀程度提供半定量指标，在诊断SS中有重要价值。 |
| 英文摘要: |
| Objective To explore the value of salivary glands ultrasonography in diagnosis of Sj gren's syndrome (SS). Methods Ninety-two patients with symptoms of xerophthalmia or xerostomia were enrolled, and 42 of them were divided to the SS group and the others to non-SS group. The bilateral parotid and submandibular gland of all patients were examined with ultrasonography, then the ultrasonographic features of bilateral salivary glands were obtained. The imaging features of salivary glands were evaluated by a semi-quantitative scoring system. The differences of ultrasonography scores between SS group and non-SS group were compared. The value of semi-quantitative scoring system in diagnosis of SS was analyzed. Results Salivary gland ultrasonic manifestations of 38 patients (38/50, 76.00%) in non-SS group were normal, whose ultrasonographic scores were 0. Whereas the ultrasound of 32 patients (32/42, 76.19%) were abnormalities in SS group, whose ultrasonographic scores were ≥ 1. Ultrasonographic scores in SS group were higher than that of non-SS group (P<0.001). The area under the ROC curve of ultrasound score in diagnosis of SS was 0.805 (P<0.001, 95% confidence interval was[0.711,0.899]). When the cutoff value of the scores was 2, the sensitivity and specificity were 59.5%, and 92.0%. Conclusion The ultrasonographic scoring of salivary glands can provide a semi-quantitative index for inhomogeneity of the salivary glands, which has significant value in the diagnosis of SS. |
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