张丽,童冠圣,文哲,王强,李思源,李征,蔺楠.下肢淋巴显像诊断乳糜反流性淋巴水肿[J].中国医学影像技术,2016,32(11):1731~1734
下肢淋巴显像诊断乳糜反流性淋巴水肿
Lower limb lymphoscintigraphy in diagnosis of chylous reflux lymphedema
投稿时间:2016-04-10  修订日期:2016-09-02
DOI:10.13929/j.1003-3289.2016.11.028
中文关键词:  淋巴闪烁显像  乳糜反流  淋巴水肿  放射性核素显像
英文关键词:Lymphoscintigraphy  Chylous reflux  Lymphedema  Radionuclide imaging
基金项目:
作者单位E-mail
张丽 首都医科大学附属北京世纪坛医院核医学科, 北京 100038 zhang-zli@163.com 
童冠圣 首都医科大学附属北京世纪坛医院核医学科, 北京 100038  
文哲 首都医科大学附属北京世纪坛医院核医学科, 北京 100038  
王强 首都医科大学附属北京世纪坛医院核医学科, 北京 100038  
李思源 首都医科大学附属北京世纪坛医院核医学科, 北京 100038  
李征 首都医科大学附属北京世纪坛医院核医学科, 北京 100038  
蔺楠 首都医科大学附属北京世纪坛医院核医学科, 北京 100038  
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中文摘要:
      目的 探讨双侧+单侧下肢淋巴显像诊断乳糜反流性淋巴水肿的价值。方法 回顾分析56例临床诊断为乳糜反流性淋巴水肿患者的显像结果。双下肢显像于患者双足第1、2及4、5趾间皮下缓慢注射99Tcm-右旋糖酐(99Tcm-DX),分别于10 min、1、3、6 h行从足到头的全身动态显像,观察患者双下肢淋巴管、双腹股沟、髂、腰淋巴结、胸导管及静脉角的显影情况;间隔1~7天后,于健侧足部第1、2及4、5趾间皮下缓慢注射99Tcm-DX,重点观察患侧下肢是否有显像剂出现。结果 双下肢淋巴显像显示56例患者(58侧患肢)中,48侧(48/58,82.76%)患肢淋巴管结构异常;38侧(38/58,65.52%)肢体腹股沟、髂、腰淋巴结显影数量减少或未显影;34例(34/56,60.71%)左静脉角显影出现不同程度的梗阻征象。单侧下肢显像显示58侧患肢经对侧注药后,反流部位均可见不同程度的显像剂出现。结论 双侧+单侧下肢淋巴显像可以直接、无创且动态显示乳糜反流。
英文摘要:
      Objective To explore the diagnostic value of bilateral and unilateral lower limb lymphoscintigraphy in the diagnosis of chylous reflux lymphedema. Methods The imaging data of 56 patients with lower limb chylous reflux of lymphedema were studied retrospectively. All patients underwent bilateral and unilateral lower limb lymphoscintigraphy. After injection of 99Tcm-DX into the first and last interdigital spaces of both feet, lymphoscintigraphy from foot to head was performed at 10 min, 1, 3 and 6 h intermittently. Lymphoscintigrams were analyzed for visualization lymphatics, lymph nodes, thoracic duct and angulus venosus of radiotracers in all bodies. After 1-7 days, 99Tcm-DX was injected into the normal feet and the patients were underwent lymphoscintigraphy as the same method. Whether the imaging agent appeared on contralateral abnormal lower limbs was observed. Results Bilateral lower limb lymphoscintigraphy showed that 48 (48/58, 82.76%) lymphatic vessel structure were dysplastic, 38 (38/58, 65.52%) lower limb lymph nodes were decreased or not visible and 34 (34/56, 60.71%) left thoracic duck obstructions were found. Unilateral lower limb lymphoscintigraphy showed 56 patients with 58 of lower limb chylous reflux of lymphedema. Conclusion Bilateral and unilateral lower limb lymphoscintigraphy can directly, non-invasively and dynamically discover lymphatic system abnormality.
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