| 金志斌,张玮婧,张捷,吴敏.超声评估早期类风湿关节炎手指关节滑膜炎分布特点[J].中国医学影像技术,2016,32(10):1572~1575 |
| 超声评估早期类风湿关节炎手指关节滑膜炎分布特点 |
| Ultrasound assessment of synovitis of finger joints in early rheumatoid arthritis patients |
| 投稿时间：2016-04-05 修订日期：2016-07-20 |
| DOI：10.13929/j.1003-3289.2016.10.026 |
| 中文关键词: 关节炎,类风湿 超声检查 滑膜炎 掌指关节 |
| 英文关键词:Arthritis, rheumatoid Ultrasonography Synovitis Metacarpophalangeal joints |
| 基金项目:南京市医学科技发展项目（YKK15076） |
|
| 摘要点击次数: 2100 |
| 全文下载次数: 1707 |
| 中文摘要: |
| 目的 采用高频超声及CDFI评估早期类风湿关节炎（RA）患者掌指关节（MCP）及近端指间关节（PIP）滑膜炎情况。方法 对34例早期RA患者340个MCP关节、340个PIP关节进行超声检查，利用灰阶超声对滑膜增生程度进行评分，并利用CDFI观察血流情况，比较不同关节以及同一关节掌侧及背侧关节面受累程度差异。结果 100个（100/340，29.41%）MCP和32个（32/340，9.41%）PIP被检出滑膜增生，差异有统计学意义（u=3.58，P<0.05）。68个MCP2中，41.18%（28/68）出现滑膜增生，68个PIP3中13.23%（9/68）出现滑膜增生，各MCP及PIP间受累程度差异无统计学意义（Hc＝3.66、2.02，P均>0.05）；MCP主要是以背侧滑膜增生为主（70/100，70.00%），PIP以掌侧增生（18/32，56.25%）明显（χ2=25.02，P<0.005）；MCP（18/20，90.00%）和PIP（3/5，60.00%）均以背侧血流的检出率更高，差异无统计学意义（P=0.166）。结论 高频超声结合CDFI可对RA患者指关节活动性滑膜炎进行评估，临床重点观察MCP背侧滑膜炎情况的诊断意义更大。 |
| 英文摘要: |
| Objective To evaluate the synovitis of the metacarpophalangeal (MCP) and proximal interphalangeal (PIP) joints in early rheumatoid arthritis (RA) by high-resolution ultrasound and CDFI.Methods Totally 680 MCP and PIP joints in 34 patients with early stage of RA were enrolled in this study. Totally of 340 MCP and 340 PIP joints were scored with ultrasound in B-mode application. The synovial vascularizations were obversved by CDFI. The difference of synovitis involved in different joints were evaluated as well as the joint between the dorsal and palmar side.Results More MCP (100/340, 29.41%) joints were identified with synovial hypertrophy than PIP (32/340, 9.41%), and the difference had statistical significance (u=3.58, P<0.05), MCP2 (28/68, 41.18%) and PIP3 (9/68, 13.23%) were mostly affected. However, no statistical significant differences were obtained in synovial grading pattern of each MCP or PIP (Hc=3.66, 2.02, all P>0.05). Synovial abnormalities were detected significantly more often on the dorsal side in MCP (70/100, 70.00%), and on palmar side (18/32, 56.25%) in PIP (χ2=25.02, P<0.005). Synovial vascularisation were observed more often on the dorsal side both in MCP (18/20, 90.00%) and PIP (3/5, 60.00%; P=0.166).Conclusion High-frequency ultrasound and color Doppler imaging has the potential to provide useful grading of synovial inflammatory process in RA patients. The dorsal side of MCP may have more value in diagnosis. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
