| 龙叶,刘建军,武新宇,李晓飞,高永举,徐俊玲,丁德刚.18F-FDG符合线路显像与增强CT诊断[J].中国医学影像技术,2016,32(8):1250~1254 |
| 18F-FDG符合线路显像与增强CT诊断 |
| Comparison of 18F-FDG dual-head coincidence imaging with enhanced CT in genitourinary tumors |
| 投稿时间：2016-01-14 修订日期：2016-05-13 |
| DOI：10.13929/j.1003-3289.2016.08.026 |
| 中文关键词: 泌尿生殖系统肿瘤 体层摄影术,X线计算机 正电子发射型体层摄影术 氟脱氧葡萄糖18F |
| 英文关键词:Genitourinary neoplasms Tomography, X-ray computed Positron-emission tomography Fluorodeoxyglucose F18 |
| 基金项目:2013年国家临床重点专科建设项目（2013-544）。 |
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| 中文摘要: |
| 目的 探讨18F-FDG符合线路显像与增强CT诊断泌尿生殖系统肿瘤的价值。方法 回顾性分析37例临床可疑泌尿生殖系统肿瘤和44例确诊泌尿生殖系统恶性肿瘤术后复查的患者，均接受FDG符合线路显像和CT增强扫描，检查间隔小于l周。分析比较两种检查对原发病灶及肿瘤转移的诊断效能。结果 37例可疑泌尿生殖系统肿瘤中恶性36例（包括肾癌11例、肾淋巴瘤3例、肾转移癌3例、肾盂癌3例、膀胱癌5例、前列腺癌8例、输尿管癌1例、阴茎癌2例），良性1例（为输尿管炎症出血），符合线路与增强CT的诊断灵敏度分别为72.22%（26/36）和83.33%（30/36）、特异度均为0，准确率分别为70.27%（26/37）和81.08%（30/37），差异无统计学意义（P=0.653）。对44例泌尿系恶性肿瘤术后复查（包括肾癌13例、肾盂癌3例、膀胱癌17例、前列腺癌5例、输尿管癌3例、阴茎癌1例、睾丸精原细胞瘤2例），16例经病理、影像或临床随访确诊远处转移，符合线路诊断效能指标均高于增强CT，但二者差异无统计学意义（χ2=0.571，P=0.453）。结论 增强CT诊断肾细胞癌和尿路上皮癌原发灶具有优势，18F-FDG符合线路显像监测恶性肿瘤术后复发转移具有较高的价值。 |
| 英文摘要: |
| Objective To explore the diagnostic value of 18F-FDG dual-head coincidence imaging and enhanced CT in genitourinary tumors. Methods The 18F-FDG dual-head coincidence imaging and enhanced CT were respectively performed within 1 week in 37 patients with clinically suspected genitourinary tumors and 44 post-operative patients with pathologically confirmed genitourinary malignant tumors. The diagnostic efficacy of two imaging modalities was analyzed and compared. Results Among the 37 patients, 36 cases were diagnosed as malignant diseases (including 11 cases of renal cell cancer, 3 of lymphoma, 3 of metastatic renal carcinoma, 3 of renal pelvic carcinoma, 5 of urinary bladder cancer, 8 of prostate cancer, 1 of ureter cancer and 2 of penile cancer), and 1 case of benign tumor (ureter hemorrhage secondary to inflammation). The sensitivity of coincidence imaging and enhanced CT scan was 72.22% (26/36) and 83.33% (30/36), respectively, and the specificity was 0 for both, and the accuracy was 70.27% (26/37) and 81.08% (30/37), respectively. The difference was not statistically significant (P=0.653). Among the 44 patients with malignant tumors who underwent operations (including 13 cases of renal cell cancer, 3 of renal pelvic cancer, 17 of urinary bladder cancer, 5 of prostate cancer, 3 of ureter cancer, 1 of penile cancer and 2 of testicular germ cell cancer), 16 cases were finally diagnosed as distant metastases. The diagnostic effectiveness of coincidence imaging was higher than that of enhanced CT scan for 44 post-operative patients, but the difference was not statistically significant (χ2=0.571, P=0.453). Conclusion Enhanced-CT scan has diagnostic advantage to identify primary lesions of renal cell carcinomas and urothelial cancers. The 18F-FDG dual-head coincidence imaging is highly valuable for monitoring postoperative relapses and metastases. |
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