| 李洋,郝大鹏,石祥龙,刘吉华,徐文坚.鼻眶部原始神经外胚层肿瘤的CT及MRI表现[J].中国医学影像技术,2016,32(5):717~721 |
| 鼻眶部原始神经外胚层肿瘤的CT及MRI表现 |
| CT and MRI findings of primitive neuroectodermal tumor in sinonasal and orbital region |
| 投稿时间：2015-11-26 修订日期：2016-03-23 |
| DOI：10.13929/j.1003-3289.2016.05.022 |
| 中文关键词: 神经外胚瘤,原始 鼻眶部 体层摄影术,X线计算机 磁共振成像 |
| 英文关键词:Neuroectodermal tumors, primitive Sinonasal and orbital region Tomography, X-ray computed Magnetic resonance imaging |
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| 中文摘要: |
| 目的 分析鼻眶部原始神经外胚层肿瘤(PNET)的CT和MRI表现。方法 回顾性分析8例经手术病理证实的鼻眶部PNET的CT和MRI征象。结果 8例肿瘤均位于鼻眶部并向颅底或颅内浸润,呈不规则状、边缘不清。CT表现:6例病变主体呈等密度,2例呈稍低密度,内部密度欠均匀;8例肿瘤均呈纵向生长,周围骨质呈明显溶骨性破坏,突破筛板侵及颅内,脑组织受累6例,于前颅凹形成肿块5例,于中颅凹形成肿块2例。MRI表现:8例肿瘤主体T1WI呈等信号5例,低信号3例,T2WI呈等信号2例,高信号6例。MRI增强示明显不均匀强化。1例MR动态增强扫描时间-强度曲线呈速升-平缓型。结论 儿童、青年患者发生累及鼻眶部的实性肿块,内部伴坏死灶、呈不均匀明显强化,沿纵轴生长侵犯硬脑膜以及易向颅底、颅内转移是鼻眶部PNET较具特征性的表现。 |
| 英文摘要: |
| Objective To investigate the CT and MRI manifestations of primitive neuroectodermal tumor (PNET) in sinonasal and orbital region. Methods The CT and MRI features of eight patients of PNET in sinonasal and orbital region with histo-pathologically confirmed were analyzed retrospectively. Results All eight irregular tumor with ill-defined margin occured in the sinonasal and orbital region and extended to skull base and intracalvarium. On CT scanning, six tumors showed iso density and two showed hypo density, all contained patchy inhomogeneous density areas. All eight tumors showed soft tissue mass appeared as longitudinal growth, and the bone destruction was mainly osteolytic destruction. All eight lesions destroyed sieve plate, and then involved brain tissue (n=6), anterior cranial fossa (n=5) and middle cranial fossa (n=2). On MRI scanning, the tumors appeared as iso (n=5) or long signal (n=3) on T1WI, iso (n=2) or long (n=6) signal on T2WI in eight cases. Inhomogeneous enhancement was seen on contrast-enhanced scan in five cases. Enhancement was showed indura (n=5) and cavemous sinus (n=2). The lesion which obtained dynamic contrast MRI showed rapidly enhancing and slow washout pattern on the time-intensity curves. Conclusion Tumor appears as longitudinal growth, remarkably inhomogeneous enhancement, involves the duramater, extends to skull base and intracalvarium, all are the typical features of PNET in sinonasal and orbital region. |
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