| 蔡华崧,王猛,翟凤仪,周丽莎,罗宴吉,郑可国,李子平,冯仕庭.两种不同激励脉冲角度对肝脏Gd-EOB-DTPA增强MRI肝细胞期病灶检出的比较[J].中国医学影像技术,2016,32(1):129~133 |
| 两种不同激励脉冲角度对肝脏Gd-EOB-DTPA增强MRI肝细胞期病灶检出的比较 |
| Lesion detection at hepatocyte phase on enhanced MRI with Gd-EOB-DTPA: Comparison of two flip angles |
| 投稿时间：2015-04-27 修订日期：2015-10-31 |
| DOI：10.13929/j.1003-3289.2016.01.033 |
| 中文关键词: 钆塞酸二钠 对比剂 翻转角 肝细胞期 磁共振成像 |
| 英文关键词:Gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid Contrast media Flip angle Hepatocyte phase Magnetic resonance imaging |
| 基金项目:国家自然科学基金(81571750)、广东省自然科学基金(2014A030311018、2014A030310484、2015A030313043)、广东省科技计划项目(2014A020212125)。 |
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| 中文摘要: |
| 目的 比较高、低翻转角(FA)对Gd-EOB-DTPA增强MRI肝细胞期病灶对比度及检出率的影响。方法 对59例肝脏局灶性病变患者均行T1W和T2W平扫、Gd-EOB-DTPA动态增强扫描及肝细胞期扫描,其中肝细胞期分别采用低FA(10°)、高FA(35°)扫描。将病灶分为总病灶组、大病灶(直径≥10 mm)组和小病灶(3 mm≤直径<10 mm)组。比较两种FA时病灶检出评分、病灶检出率及病灶-肝脏CNR。结果 Gd-EOB-DTPA增强扫描肝细胞期高FA T1WI病灶检出评分高于低FA T1WI病灶检出评分,其中高、低FA时,总病灶组与小病灶组的检出病灶评分差异有统计学意义(P<0.05),而与大病灶组的差异无统计学意义(P>0.05)。高FA T1WI病灶检出率高于低FA T1WI病灶检出率,其中总病灶组与小病灶组的差异有统计学意义(P<0.05),而与大病灶组的差异无统计学意义。低、高FA的肝脏-病灶CNR分别为75.24±10.33、147.81±9.26,差异有统计学意义(P<0.001)。结论 Gd-EOB-DTPA增强肝细胞期扫描时,采用高FA可获得高质量的图像,有利于病灶的检出。 |
| 英文摘要: |
| Objective To compare the effect of high and low flip angles (FA) on CNR and detection rate of lesions in hepatocyte phase in MRI with Gd-EOB-DTPA. Methods Fifty-nine patients with focal liver lesions were enrolled. All the patients underwent plain scan and Gd-EOB-DTPA-enhanced T1W and T2W scan including dynamic phase, hepatocellular phase (HP). The HP was performed at low FA (10°) and high FA (35°) respectively. Lesions were divided into three groups, including the "all lesions" group, the "large lesions" group (diameter≥10 mm) and the "small lesions" group (3 mm≤diameter<10 mm). Detection score of lesions, detection rate of lesions and CNR were compared. Results The detection score of lesions at high FA was higher than that at low FA (P<0.05), and there was statistically significant difference in "all lesions" group and "small lesions" group in both high and low FA (P<0.05), but there was no statistically significant difference between "all lesions" group and "large lesions" group. The detection rate of lesions at high FA was also higher than that at low FA, and there was statistically significant difference in "all lesions" group and "small lesions" group in high FA (P<0.05), but there was no statistically significant difference between "all lesions" group and "large lesions" group. The CNR at low FA and high FA was 75.24±10.33 and 147.81±9.26, respectively (P<0.001). Conclusion Increasing the FA from 10° to 35° at hepatocyte phase in MRI with Gd-EOB-DTPA can improve the CNR of liver lesions and detection rate. |
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