张立华,袁慧书,杨邵敏,孔令红,姜亮,刘晓光.脊柱腱鞘巨细胞瘤影像和病理特征[J].中国医学影像技术,2016,32(1):117~120
脊柱腱鞘巨细胞瘤影像和病理特征
Imaging and pathological appearances of giant cell tumor of tendon sheath of spine
投稿时间:2015-03-09  修订日期:2015-04-16
DOI:10.13929/j.1003-3289.2016.01.030
中文关键词:  脊柱  巨细胞瘤  腱鞘  体层摄影术,X线计算机  磁共振成像
英文关键词:Spine  Giant cell tumor  Tendon sheath  Tompgraphy,X-ray computed  Magnetic resonance imaging
基金项目:
作者单位E-mail
张立华 北京大学第三医院放射科, 北京 100190  
袁慧书 北京大学第三医院放射科, 北京 100190 huishuy@sina.com 
杨邵敏 北京大学第三医院病理科, 北京 100190  
孔令红 北京大学第三医院病理科, 北京 100190  
姜亮 北京大学第三医院骨科, 北京 100190  
刘晓光 北京大学第三医院骨科, 北京 100190  
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中文摘要:
      目的 探讨脊柱腱鞘巨细胞瘤(GCTTS)的CT和MRI的影像学及病理学表现。方法 对7例病理学检查确诊的脊柱GCTTS影像学表现进行回顾性分析。结果 GCTTS位于颈椎5例,胸椎2例。CT表现为寰枢外侧关节(n=3)、C6~7左侧小关节(n=1)、C5椎体及右侧附件(n=1)、胸椎椎体(n=2)呈溶骨性骨破坏;肿瘤压迫、侵蚀性邻近骨质,骨破坏区周围可见硬化边(n=5)。MR示肿瘤呈分叶状,T2WI呈低信号5例,中等信号1例(位于T11),混杂信号1例;增强扫描肿瘤呈中等程度或明显均匀强化。结论 脊柱GCTTS以小滑膜关节多见,对邻近骨质压迫侵蚀,周围硬化边较多见;T2WI低信号是其特征性表现;以良性多见,若肿瘤内部囊变坏死明显,应警惕恶性可能。
英文摘要:
      Objective To explore the imaging findings and pathological appearances of giant cell tumor of tendon sheath (GCTTS) of spine. Methods The imaging appearances of GCTTS in 7 cases of spine confirmed by surgical operation and pathological diagnosis were retrospectively analyzed. Results Five cases were located in cervical spine and 2 cases in thoracic spine. CT manifestations included osteolytic bone destruction in the lateral atlantoaxial joint (n=3), C6-7 left side small joints (n=1), C5 vertebral body and right side of accessory (n=1), thoracic vertebral body (n=2).Tumors compressed and eroded the adjacent bone, with sclerosis rim formation in 5 cases. MRI showed lobulated tumors, 5 cases showed low signal on T2WI, 1 located in T11 showed homogeneous moderate signal and 1 located in C1-2 showed heterogeneous signal. All lesions showed moderate to significant enhancement. Conclusion GCTTS mostly locates at small synovial joint, compresses and erodes the adjacent bone. Low signal is characteristic on T2WI. Most of GTCS are benign, if cystic changes or necrosis are obvious in the tumor, the possibility of malignancy should be noted.
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