张蓉琴,尹吉林,李向东,王欣璐,张金赫,柳伟坤.18F-FDG PET/CT显像诊断不明原因腹腔积液[J].中国医学影像技术,2016,32(1):79~82 |
18F-FDG PET/CT显像诊断不明原因腹腔积液 |
18F-FDG PET/CT in evaluation of ascites of undetermined origin |
投稿时间:2015-05-12 修订日期:2015-07-29 |
DOI:10.13929/j.1003-3289.2016.01.021 |
中文关键词: 腹腔积液 癌 腹膜,结核 放射性核素显像 氟脱氧葡萄糖F18 |
英文关键词:Ascites Carcinoma Peritonitis,tuberculous Radionuclide imaging Fluorodeoxyglucose F 18 |
基金项目:广东省教育部产学研结合项目(2012B091100172)、广东省自然科学基金(S2012010010685)。 |
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中文摘要: |
目的 探讨18F-FDG PET/CT显像对不明原因腹腔积液患者的诊断价值。方法 回顾性分析96例不明原因腹腔积液患者的PET/CT资料,将病理及临床随访结果与PET/CT进行对照。结果 96例患者中,75例为腹膜恶性肿瘤(腹膜转移瘤69例,腹膜间皮瘤4例,假黏液瘤2例);21例为良性腹膜炎(17例腹膜结核,4例细菌性腹膜炎)。PET/CT诊断腹膜良恶性病变的灵敏度、特异度和准确率分别为94.67%(71/75)、71.43%(15/21)和89.58%(86/96)。腹膜良、恶性病变的SUVmax分别为7.91±4.01和6.03±3.19(t=-2.25,P<0.05)。18F-FDG代谢范围与CT病灶范围的比较对鉴别腹膜良恶性病变差异有统计学意义(χ2=35.36,P<0.01)。结论 18F-FDG PET/CT在鉴别良恶性腹腔积液方面有重要价值,尤其是对肿瘤原发灶的检出,但在诊断腹膜结核时易引起假阳性,故应当密切结合临床资料和其他检查以减少误诊。 |
英文摘要: |
Objective To evaluate the value of 18F-FDG PET/CT in diagnosis of ascites of undetermined origin. Methods Totally 96 patients with ascites of undetermined origin were retrospectively analyzed. The PET/CT imaging results were compared with pathology and clinical follow-up reports. Results There were 75 patients with malignant diseases including peritoneal metastasis (n=69), peritoneal mesothelioma (n=4) and pseudomyxoma peritone (n=2), and 21 with benign peritonitis including peritoneal tuberculosis (n=17) and bacterial peritonitis (n=4). The sensitivity, specificity, and accuracy of PET/CT in detecting the cause of ascites were 94.67% (71/75), 71.43% (15/21) and 89.58% (86/96), respectively. SUVmax was statistical significance between peritoneal benign and malignant lesions (7.91±4.01 vs 6.03±3.19; t=-2.25, P<0.05). There was also statistical significance to compare the scope of 18F-FDG and CT in the diagnosis of ascites (χ2=35.36, P<0.01). Conclusion 18F-FDG PET/CT offers higher value in the differential diagnosis of ascites, especially in detecting the primary tumor. In the diagnosis of peritoneal tuberculosis, 18F-FDG PET/CT can lead to a false positive, which should be closely combined with clinical data and other checks to reduce misdiagnosis. |
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