| 陈潭辉,佘德君,曹代荣,邢振,杨谢峰.灌注加权成像鉴别诊断毛细胞型星形细胞瘤和血管母细胞瘤[J].中国医学影像技术,2016,32(1):17~20 |
| 灌注加权成像鉴别诊断毛细胞型星形细胞瘤和血管母细胞瘤 |
| Perfusion weighted imaging in differential diagnosis of pilocytic astrocytomas and hemangioblastomas |
| 投稿时间：2015-04-15 修订日期：2015-09-25 |
| DOI：10.13929/j.1003-3289.2016.01.004 |
| 中文关键词: 毛细胞型星形细胞瘤 血管母细胞瘤 磁共振成像 诊断显像 |
| 英文关键词:Pilocytic astrocytomas Hemangioblastomas Magnetic resonance imaging Diagnostic imaging |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨PWI对毛细胞型星形细胞瘤(PA)和血管母细胞瘤(HB)的鉴别诊断价值。方法 回顾分析经手术病理证实的26例PA与16例HB患者的常规MR平扫、PWI及增强扫描资料。计算PA和HB瘤体的相对脑血容量(rCBV)、信号强度-时间曲线的相对信号恢复率(rPSR)。采用独立样本t检验、Z检验及ROC曲线进行统计学分析。结果 PA的rCBV值明显低于HB(1.79±0.99,8.69±2.66),rPSR值明显高于HB(0.99±0.25,0.48±0.28),差异均有统计学意义(P均<0.01)。当rCBV值>3.95或rPSR值≤0.71诊断HB时,rCBV值较rPSR的准确率高。rCBV和rPSR的曲线下面积分别为1.00、0.90(Z=1.995,P<0.05)。结论 PWI有助于PA和HB的鉴别诊断。 |
| 英文摘要: |
| Objective To explore the value of PWI in differential diagnosis of pilocytic astrocytomas (PA) and hemangioblastomas (HB). Methods Totally 26 patients with PA and 16 patients with HB confirmed by surgery and pathology underwent conventional MRI, PWI and enhanced MRI. And the imaging data were retrospectively analyzed. Relative cerebral blood volume (rCBV) and relative percentage of signal intensity recovery (rPSR) of signal intensity-time curve were calculated. Independent samples t test, Z test and ROC curve were adopted for statistical analysis. Results The rCBV value in PA was significantly lower than that in HB (1.79±0.99 vs 8.69±2.66), while the rPSR value in PA was significantly higher than that in HB (0.99±0.25 vs 0.48±0.28), and the statistical difference were both significant (both P<0.01). Taking rCBV>3.95 or rPSR≤0.71 diagnosis of HB, the accuracy of rCBV (42/42, 100%) was higher than that of rPSR (37/42, 88.10%). The area under curve of rCBV was significantly higher than that of rPSR (1.00 vs 0.90, Z=1.995, P<0.05). Conclusion PWI is helpful for differential diagnosis of PA and HB. |
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