| 林燕,杨学东,马占姝,王蕊,林志勇,王霄英.CT值不均匀度诊断肾透明细胞癌[J].中国医学影像技术,2015,31(12):1894~1897 |
| CT值不均匀度诊断肾透明细胞癌 |
| CT value heterogeneity of tumor for clear cell renal cell carcinoma |
| 投稿时间：2015-04-27 修订日期：2015-10-19 |
| DOI：10.13929/j.1003-3289.2015.12.032 |
| 中文关键词: 癌,肾细胞 体层摄影术,X线计算机 CT值 |
| 英文关键词:Carcinoma, renal cell Tomography, X-ray computed CT value |
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| 中文摘要: |
| 目的 探讨CT值不均匀度鉴别诊断肾透明细胞癌的价值。方法 回顾性分析经术后病理证实为肾细胞癌患者的CT图像,纳入169个肿瘤,分为透明细胞癌组(n=152)和乏血供肾细胞癌组(n=17)。测量CT值的标准差,同时测量皮髓质期和实质期肿瘤的CT值,及同层面正常肾脏皮质和腹主动脉的CT值并获得CT值比值参数: 皮髓质期肿瘤CT值/正常肾脏皮质CT值(TCOCM),皮髓质期肿瘤CT值/腹主动脉CT值(TAOCM),以及实质期肿瘤CT值/正常肾脏皮质CT值(TCON)、实质期肿瘤CT值/腹主动脉CT值(TAON)。对两组以上参数进行统计学分析。结果 皮髓质期透明细胞癌组的CT值标准差(29.60±9.57)高于乏血供肾细胞癌组(18.85±8.10;t=－4.46,P<0.001)。平扫和实质期两组肿瘤CT值标准差差异均无统计学意义(P均>0.05)。皮髓质期的CT值标准差与透明细胞癌的Fuhrman分级存在弱相关(r=－0.16,P=0.049)。透明细胞癌组的TCOCM、TAOCM、TCON、TAON均高于乏血供肾细胞癌(P均<0.05)。结论 肾透明细胞癌皮髓质期的CT值标准差高,且CT值标准差可能与Fuhrman分级相关。CT值标准差可作为反映透明细胞癌皮髓质期不均匀强化的定量指标。 |
| 英文摘要: |
| Objective To explore the value of CT value heterogeneity on differential diagnosis of clear cell renal cell carcinoma. Methods Totally 169 renal cell carcinomas were enrolled, which were divided into clear cell carcinoma group (CCC group, n=152) and renal cell carcinoma with minimal blood supply (RCCWMBS group, n=17), and the standard deviations (SD) of CT value for tumor were measured. CT value of tumor in coticomedullary phase and nephrographic phase, as well as of the normal renal cortex and aorta in both phases were also measured. CT value parameters were generated: Tumor/cortex of corticomedullay phase (TCOCM), tumor/aorta of corticomedullay phase (TAOCM), as well as tumor/cortex of nephrographic phase (TCON), tumor/aorta of nephrographic phase (TAON). Statistical analysis was performed. Results SD of CCC group (29.60±9.57) was higher than that in RCCWMBS group (18.85±8.10; t=－4.46, P<0.001). The SD in plain phase and nephrogarphic phase showed no differences in both groups (both P>0.05). The SD in corticomedullary phase was correlated weakly with Fuhrman grade in CCC group (r=－0.16, P=0.049). The TCOCM, TAOCM, TCON as well as TAON in CCC group were significantly higher than those in RCCWMBS group (all P<0.05). Conclusion The SD of CT value of CCC in corticomedullary phase is higher, and SD may correlate with Fuhrman grade. The SD of CT value can serve as a quantitative parameter to reflect the enhancement heterogeneity of CCC in corticomedullary phase. |
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