| 赵飞飞,吕富荣,肖智博,吕发金,李佳,屈亚林.动态增强MRI Reference region模型在子宫肌瘤中的初步应用[J].中国医学影像技术,2015,31(12):1861~1865 |
| 动态增强MRI Reference region模型在子宫肌瘤中的初步应用 |
| Preliminary study of dynamic contrast-enhanced MRI reference region model in uterine fibroids |
| 投稿时间：2015-04-30 修订日期：2015-10-07 |
| DOI：10.13929/j.1003-3289.2015.12.023 |
| 中文关键词: 子宫肌瘤 磁共振成像 动态增强 Reference region模型 |
| 英文关键词:Uterine fibroids Magnetic resonance imaging Dynamic contrast enhanced Reference region model |
| 基金项目:国家临床重点专科建设项目(2013544)、重庆市渝中区科技计划项目(20120211)。 |
|
| 摘要点击次数: 3805 |
| 全文下载次数: 879 |
| 中文摘要: |
| 目的 探讨动态增强MRI(DCE-MRI)评价子宫肌瘤血流动力学情况的应用价值。方法 对61例子宫肌瘤患者(78个子宫肌瘤)行DCE-MRI,选择Reference region模型完成图像后处理;对肌瘤特点、肌瘤及肌层定量参数值行统计学分析;将子宫肌瘤Rktrans、Kep,RR、Kep,TOI值与患者自身肌层相应值作比较,高于(或低于)肌层相应值者定义为高(或低)Rktrans、Kep,RR、Kep,TOI病灶;依据T2WI图像上肌瘤信号强度分为低信号、等信号、不均匀高信号、均匀显著高信号、均匀轻度高信号。结果 子宫肌瘤与肌层间Rktrans、Kep,RR、Kep,TOI值的差异均有统计学意义(P均< 0.05);高Rktrans病灶与低Rktrans病灶、高Kep,TOI病灶与低Kep,TOI病灶差异有统计学意义(P均< 0.05),高Kep,RR病灶与低Kep,RR病灶差异无统计学意义(P> 0.05);肌瘤T2WI信号强度与其Rktrans、Kep,RR、Kep,TOI值呈低度正相关(r值分别为0.308、0.303、0.318,P均< 0.05)。均匀轻度高信号肌瘤Rktrans值与低、等、不均匀高、均匀显著高信号肌瘤间Rktrans值的差异有统计学意义(P均< 0.05);均匀轻度高信号肌瘤Kep,RR值与低、等信号肌瘤Kep,RR值间差异有统计学意义(P均< 0.05);均匀轻度高信号肌瘤Kep,TOI值与低、等、不均匀高信号肌瘤Kep,TOI值间差异有统计学意义(P均< 0.05),低信号肌瘤Kep,TOI值与均匀显著高信号肌瘤Kep,TOI值差异有统计学意义(P=0.027);余组间比较差异均无统计学意义(P均> 0.05)。肌壁间、浆膜下、黏膜下肌瘤间Rktrans、Kep,RR、Kep,TOI值的差异均无统计学意义(P均> 0.05)。结论 DCE-MRI的Reference region模型可用以定量分析子宫肌瘤与子宫肌层不同的血流动力学特点。 |
| 英文摘要: |
| Objective To investigate the application value of dynamic contrast enhanced MRI (DCE-MRI) in assessing the hemodynamic change of uterine fibroids. Methods Sixty-one patients with 78 uterine fibroids underwent dynamic contrast enhanced MRI examinations, and the characteristics of pharmacokinetics parameter between uterine leiomyoma and myometrium with Reference region model for MR image post-processing were analyzed. Also the statistical analysis was carried out in the quantitative parameters of uterine fibroids and the characteristics of the myoma. According to the value of Rktrans, Kep,RR and Kep,TOI, these uterine fibroids were divided into high group and low group, respectively. Uterine fibroids were classified as five types on pretreatment T2-weighted MRI, i.e. hypointense, isointense, heterogeneous hyperintense, markedly homogenous hyperintense, slightly homogenous hyperintense. Results Significant differences of Rktrans, Kep,RR and Kep,TOI value were found between the uterine fibroids and the myometrium. There was statistical difference between the of high Rktrans and low Rktrans groups, high Kep,TOI and low Kep,TOI groups (all P< 0.05), no significant differences were found between high Kep,RR and low Kep,RR group (all P> 0.05). The T2WI signals of the myomas were positively correlated with the Rktrans, Kep,RR and Kep,TOI value of the uterine fibroids (r=0.308, 0.303, 0.318, all P< 0.05). Significant differences were found between the Rktrans values of slightly homogenous hyperintense and the other four groups, the Kep,RR values of slightly homogenous hyperintense and hypointense, isointense, the Kep,TOI values of slightly homogenous hyperintense and other four groups except markedly homogenous hyperintense, the Kep,TOI values of hypointense and markedly homogenous hyperintense (P< 0.05). Conclusion DCE-MRI with Reference region model can be used to quantitatively analyze hemodynamic characteristics of uterine fibroids and myometrium. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
