| 马荣政,孙洪赞,辛军,郭启勇.18F-FDG PET/CT观察慢性肝炎及肝硬化患者肝脏葡萄糖代谢功能变化[J].中国医学影像技术,2015,31(12):1848~1851 |
| 18F-FDG PET/CT观察慢性肝炎及肝硬化患者肝脏葡萄糖代谢功能变化 |
| 18F-FDG PET/CT finding of liver glucose metabolic changes in patients with chronic hepatitis and cirrhosis |
| 投稿时间：2015-03-25 修订日期：2015-11-04 |
| DOI：10.13929/j.1003-3289.2015.12.019 |
| 中文关键词: 肝炎,乙型,慢性 肝硬化 代谢 葡萄糖 正电子发射型体层摄影术 |
| 英文关键词:Hepatitis B, chronic Liver cirrhosis Metabolism Glucose Positron-emission tomography |
| 基金项目:国家自然科学基金青年基金项目(81401438)、辽宁省教育厅科学研究一般项目(L2014308)。 |
|
| 摘要点击次数: 4159 |
| 全文下载次数: 711 |
| 中文摘要: |
| 目的 探讨应用18F-FDG PET/CT观察慢性肝炎及肝硬化患者肝脏葡萄糖代谢功能变化的价值。方法 回顾性分析50例慢性肝炎患者(肝炎组)、36例肝硬化患者(肝硬化组)及31例肝功能正常者(对照组)的18F-FDG PET/CT资料。比较肝炎组、肝硬化组及对照组全肝平均标准摄取值(SUVmean)、全肝体积(HV)及全肝糖酵解值(GHG)的差异。结果 3组间全肝SUVmean及GHG差异均有统计学意义(P均< 0.01)。肝硬化组SUVmean及GHG低于肝炎组(P均< 0.001)及对照组(P=0.012、0.014),肝炎组SUVmean及GHG高于对照组(P=0.042、0.046)。3组间HV差异无统计学意义(P=0.58)。结论 18F-FDG PET/CT检查指标全肝SUVmean及GHG可有效反映慢性肝炎及肝硬化患者肝脏葡萄糖代谢功能变化。 |
| 英文摘要: |
| Objective To explore the value of 18F-FDG PET/CT in observing hepatic glucose metabolism function changes of chronic hepatitis and liver cirrhosis. Methods 18F-FDG PET/CT data of 117 subjects including 50 patients with chronic hepatitis (hepatitis group), 36 patients with liver cirrhosis (cirrhosis group) and 31 patients without chronic hepatitis or liver cirrhosis (control group) were retrospectively analyzed. Total hepatic mean standardized uptake value (SUVmean), hepatic volumes (HV) and global hepatic glycolysis (GHG) were compared among different groups. Results There were statistical differences of SUVmean and GHG among three groups (all P< 0.01). SUVmean and GHG in cirrhosis group were lower than those in hepatitis group (both P< 0.001) and control group (P=0.012, 0.014). While SUVmean and GHG in hepatitis group were higher than those in control group (P=0.042, 0.046). No statistical difference HV was found (P=0.58). Conclusion 18F-FDG PET/CT indexes as total SUVmean and GHG can effectively reflect the changes of hepatic glucose metabolism function in patients with chronic hepatitis or liver cirrhosis. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
