| 赵冰冰,曲绍辉,田家玮.三维斑点追踪技术评价不同时期慢性肾病患者左心室收缩功能[J].中国医学影像技术,2015,31(12):1830~1834 |
| 三维斑点追踪技术评价不同时期慢性肾病患者左心室收缩功能 |
| Three-dimensional speckle tracking imaging on evaluation of left ventricular function in patients with different stages of chronic kidney disease |
| 投稿时间：2015-04-19 修订日期：2015-09-22 |
| DOI：10.13929/j.1003-3289.2015.12.015 |
| 中文关键词: 超声心动描记术,三维 三维斑点追踪成像 慢性肾病 左心室收缩功能 |
| 英文关键词:Echocardiography, three-dimensional Three-dimensional speckle tracking imaging Chronic kidney disease Left ventricular contract function |
| 基金项目: |
|
| 摘要点击次数: 3965 |
| 全文下载次数: 821 |
| 中文摘要: |
| 目的 采用三维斑点追踪技术(3D-STI)评价不同时期慢性肾病(CKD)患者的左心室收缩功能。方法 收集90例CKD患者并按肾小球滤过率将其分为早期组、中期组、晚期组,各30例,另选取30名健康人作为对照组。均采用3D-STI测量左心室整体纵向应变(GLS)、左心室整体径向应变(GRS)、左心室整体圆周应变(GCS)及左心室整体面积应变(GAS),比较4组间的差异。绘制ROC曲线,评价采用GLS及GAS检测早期CKD患者左心室收缩功能异常的敏感度及特异度。结果 ①与对照组相比,3组CKD患者的GLS和GAS均降低(P均<0.05);晚期组GLS、GAS较早期组减低(P均<0.05);②ROC曲线分析:采用GAS判定早期CKD患者左心室收缩功能异常的ROC曲线下面积为0.85,以－30.5为截断值时,其敏感度为88.5%,特异度为81.0%;而采用GLS时的ROC曲线下面积为0.67,以－18.5为截断值时,其敏感度为84.6%,特异度为80.0%。结论 3D-STI可用以评价不同时期CKD患者的左心室收缩功能,其中GLS、GAS是诊断其收缩功能较好的指标,并可为早期检测出CKD患者左心室收缩功能异常提供定量指标。 |
| 英文摘要: |
| Objective To evaluate the left ventricular (LV) function in patients with different stages of chronic kidney disease (CKD) by three-dimensional speckle tracking imaging (3D-STI). Methods Totally 90 patients with CKD were collected, and then according to glomerular filtration rate (GFR), the CKD patients were divided into three groups, i.e, CKD 1-2 (n=30), CKD 3 (n=30), CKD 4-5 (n=30), and 30 healthy persons were recruited as control group. All participants were performed 3D-STI to get global longitudinal peak systolic strain (GLS), global radial peak systolic strain (GRS), global circular peak systolic strain (GCS), global area peak systolic strain (GAS), and then the difference among 4 group were compared. The sensitivity and specificity of GLS and GAS in diagnosing the left ventricular systolic function of patients with CKD were analyzed by the ROC curve. Results ①Compared with control group, GLS and GAS of CKD 1-2, CKD 3 and CKD 4-5 groups decreased significantly (all P<0.05). There were differences in GLS and GAS between CKD 1-2 and CKD 4-5 groups (both P<0.05). ②The area under ROC curve was 0.85, and the sensitivity and specificity of GAS in diagnosing the left ventricular systolic function were 88.5% and 81.0% respectively by the cut-off value of －30.5. The area under ROC curve was 0.67, and the sensitivity and specificity of GAS in diagnosing the left ventricular systolic function were 84.6% and 80.0% respectively by the cut-off value of －18.5. Conclusion 3D-STI can be used to evaluate the LV function in patients with different stages of CKD, and early detect the contract dysfunction of left ventricle in patients with chronic kidney disease. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
