| 黄克敏,冯彦林,梁伟棠,刘德军,杨明,冼伟均,李林,冯叶霞,邓大浪.SPECT/CT心肌灌注显像左心室各壁段放射性分布[J].中国医学影像技术,2015,31(11):1680~1684 |
| SPECT/CT心肌灌注显像左心室各壁段放射性分布 |
| Radioactivity distributing of left ventricle in myocardial perfusion SPECT/CT imaging |
| 投稿时间：2015-01-13 修订日期：2015-07-02 |
| DOI：10.13929/j.1003-3289.2015.11.020 |
| 中文关键词: 心脏 体层摄影术,发射型计算机,单光子 衰减校正 伪影 |
| 英文关键词:Heart Tomography, emission-computed, single-photon Attenuation corrected Artificial |
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| 中文摘要: |
| 目的 探讨SPECT/CT心肌灌注显像CT衰减校正(CTAC)和无衰减校正(NOAC)图像左心室各壁段的放射性分布特征。方法 分析120例冠状动脉粥样硬化性心脏病低风险受检者99Tcm-甲氧基异丁基异腈静息心肌灌注显像,均行CTAC。重建CTAC和NOAC图像。利用靶心图获得CTAC和NOAC图像左心室各壁段的放射性计数百分比,比较CTAC和NOAC图像左心室各壁段放射性计数和图像的差异,以及在不同性别和不同体质量指数(BMI)受检者间的差异。结果 NOAC图像示男性下后壁、间壁、前壁基底段的放射性计数百分比明显低于女性(t=－8.271、－4.2555、－3.168,P均<0.05),而前壁中段及前壁心尖部则明显高于女性(t=2.047、2.627,P均<0.05)。CTAC图像示左心室下后壁、间壁和侧壁的放射性计数百分比明显增加(t=21.077、8.635、2.623,P均<0.05),其中以男性下后壁最为显著,同时心尖部和前壁心尖部的放射性计数百分比明显减低(t=－16.421、－13.891,P均<0.001),其中以高BMI受检者的心尖部最为显著。NOAC图像示,女性前壁出现放射性稀疏的受检者明显多于男性[31.67%(19/60)和13.33%(8/60);χ2=5.783,P=0.016],男性下后壁出现放射性稀疏的受检者明显多于女性[78.33%(47/60)和15.00%(9/60);χ2=48.348,P<0.001];CTAC图像示分别有60.83%(73/120)、26.67%(32/120)、22.50%(27/120)的受检者出现下后壁、间壁、侧壁放射性分布增加,其中男性下后壁放射性分布增加的受检者明显多于女性[86.67%(52/60)和35.00%(21/60);χ2=33.611,P<0.001];同时28.33%(34/120)、61.67%(74/120)的受检者出现前壁、心尖部放射性分布减低。结论 左心室各壁段的放射性分布在不同性别间存在显著差异,CTAC可明显改善左心室下后壁、间壁和侧壁的衰减伪影,其对男性的补偿作用明显优于女性。 |
| 英文摘要: |
| Objective To explore the radioactivity distributing of left ventricle in CT attenuation corrected (CTAC) and no attenuation corrected (NOAC) image of myocardial perfusion SPECT/CT. Methods The data of 120 patients were retrospectively analyzed, who had a low pretest likelihood of coronary artery disease after exercise rest 99Tcm-methoxy isobutyl isouitril (99Tcm-MIBI) myocardial perfusion SPECT and underwent CTAC on a SPECT/CT system. The CTAC and NOAC images were reconstructed for all patients. The counts of the left ventricle using myocardial Bull's-eye were measured. The image quality and semi-quantitative of the CTAC and NOAC and the difference of different sex and body mass index (BMI) were compared and analyzed. Results The counts of inferior-posterior, septal wall and anterior-basal region were significant lower (t=－8.271, －4.2555, －3.168, all P<0.05), and anterior-middle, anterior-apex region were significant higher (t=2.047, 2.627, all P<0.05)in man than those in woman on NOAC images. The counts of inferior-posterior, septal and lateral wall significant increased (t=21.077, 8.635, 2.623, all P<0.05) in CTAC images compared to NOAC images expressly in the inferior-posterior wall of man, simultaneously the counts of apex wall and anterior-apex region significantly decreased (t=－16.421, －13.891, all P<0.001) expressly in the apex wall of high BMI patients. The patients who had a anterior wall artificial were significant higher (31.67% [19/60] and 13.33% [8/60]; χ2=5.783, P=0.016) in woman than that in man, and the inferior-posterior wall artificials were significant higher (78.33% [47/60] and 15.00% [9/60], χ2=48.348, P<0.001) in man than that in woman in NOAC images. The radioactivity distributing of inferior-posterior, septal and lateral wall significant increased for 60.83% (73/120), 26.67% (32/120) and 22.50% (27/120) respectively on CTAC images, and it was significant higher (86.67% [52/60] and 35.00% [21/60], χ2=33.611, P<0.001) in man than that in woman for inferior-posterior wall, and it significantly decreased in anterior and apex wall for 28.33% (34/120) and 61.67% (74/120) patients respectively. Conclusion The radioactivity distributing of left ventricle are significant difference in different sex, and the attenuation artificial of inferior-posterior, septal and lateral wall can be significantly improved on CTAC images expressly in man. |
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