李正然,沈慧聪,常天静,范亦龙,艾林,马军,戴建平.毛细胞黏液样星形细胞瘤临床及影像学特点[J].中国医学影像技术,2015,31(11):1630~1634
毛细胞黏液样星形细胞瘤临床及影像学特点
Clinical and imaging characteristics of pilomyxoid astrocytoma
投稿时间:2015-04-16  修订日期:2015-06-15
DOI:10.13929/j.1003-3289.2015.11.006
中文关键词:  星形细胞瘤  磁共振成像  体层摄影术,X线计算机
英文关键词:Astrocytoma  Magnetic resonance imaging  Tomography, X-ray computed
基金项目:
作者单位E-mail
李正然 首都医科大学附属北京天坛医院神经影像中心, 北京 100050  
沈慧聪 首都医科大学附属北京天坛医院神经影像中心, 北京 100050 shenhuicong@126.com 
常天静 首都医科大学附属北京天坛医院神经影像中心, 北京 100050  
范亦龙 首都医科大学附属北京天坛医院神经影像中心, 北京 100050  
艾林 首都医科大学附属北京天坛医院神经影像中心, 北京 100050  
马军 首都医科大学附属北京天坛医院神经影像中心, 北京 100050  
戴建平 首都医科大学附属北京天坛医院神经影像中心, 北京 100050  
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中文摘要:
      目的 分析毛细胞黏液样星形细胞瘤(PMA)的临床及影像学特征。方法 回顾性分析35例经手术、病理及免疫组化证实的PMA患者的临床特点及影像学表现。结果 PMA主要位于下丘脑-视交叉-3脑室区域(23/35,65.71%),其次为大脑半球(6/35,17.14%)。CT扫描多为稍低密度(23/28,82.14%)和等密度(2/28,7.14%),因出血呈高密度3例(3/28,10.71%);合并少许点状、线状钙化9例。MR扫描边界清晰30例(30/31,96.78%);无瘤周水肿28例(28/31,90.32%),轻度水肿3例(3/31,9.68%)。 T1WI实性部分为不均匀稍低信号28例(28/31,90.32%)。T2WI为高信号伴絮片状稍高信号26例(26/31,83.87%),均匀高信号1例(1/31,3.23%),不均匀等信号2例(2/31,6.45%),因出血为低信号2例(2/31,6.45%);瘤体内见点、线状等信号27例(27/31,87.09%)。增强扫描,实性部分明显强化27例(27/30,90.00%),轻度点线状强化1例(1/30,3.33%),无强化2例(2/30,6.67%);实性部分包含无强化区28例(28/30,93.33%),柔脑膜强化5例(5/30,16.67%)。结论 PMA影像学表现具有一定特征性,结合临床及CT、MRI特征,可提高术前诊断的准确性。
英文摘要:
      Objective To analyse the clinical and imaging features of pilomyxoid astrocytomas (PMAs). Methods CT/MR images and medical records of 35 patients with PMAs were retrospectively reviewed. All tissue samples were independently reviewed for confirmation of pathologic diagnosis. Results PMAs were mainly located in the chiasmatic-hypothalamic-3rd ventricular region (23/35, 65.71%), the second were located in the cerebral hemisphere (6/35, 17.14%). On CT scans, most PMAs showed iso-hypodense (23/28, 82.14%) and isodense (2/28, 7.14%), 3 cases (3/28, 10.71%) showed hyperdense because of hemorrhage, 9 cases with linear and punctuate calcifications. On MR scans, 30 cases (30/31, 96.78%) appeared well-circumscribed, 28 cases (28/31, 90.32%) had no peritumoral edema, another 3 cases (3/31, 9.68%) had mild edema. The solid portions of 28 cases (28/31, 90.32%) were heterogeneous iso-hypointense on T1WI and 26 cases (26/31, 83.87%) were hyperintense with patchy iso-hyperintense on T2WI, 1 case (1/31, 3.23%) was homogeneous hyperintense, 2 cases (2/31, 6.45%) were heterogeneous isointense, 2 cases (2/31, 6.45%) showed hypointense because of hemorrhage. 27 cases (27/31, 87.09%) with linear and punctuate isointense. Upon contrast administration, the solid portions of 27 PMAs (27/30, 90.00%) enhanced intensely, 1 PMA (1/30, 3.33%) enhanced slightly, 2 cases (2/30, 6.67%) had no enhancement. 28 cases (28/30, 93.33%) containing solid mass included non-enhancing portion. Leptomeningeal enhancement was noted in 5 cases (5/30, 16.67%). Conclusion The imaging features and clinical characteristics of PMAs can be used to improve the accuracy of preoperative diagnosis.
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