梁志刚,笪宇威,康瑞莹,李坤成.肢带型肌营养不良的MRI表现[J].中国医学影像技术,2015,31(10):1574~1577
肢带型肌营养不良的MRI表现
MRI features of limb-girdle muscular dystrophies
投稿时间:2015-01-26  修订日期:2015-09-24
DOI:10.13929/j.1003-3289.2015.10.029
中文关键词:  肢带型肌营养不良  磁共振成像  诊断显像
英文关键词:Limb-girdle muscular dystrophies  Magnetic resonance imaging  Diagnostic imaging
基金项目:
作者单位E-mail
梁志刚 首都医科大学宣武医院核医学科, 北京 100053  
笪宇威 首都医科大学宣武医院神经内科, 北京 100053  
康瑞莹 北京市丰台区丰台社区卫生服务中心, 北京 100071  
李坤成 首都医科大学宣武医院放射科, 北京 100053 15699959692@163.com 
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中文摘要:
      目的 观察肢带型肌营养不良的MRI表现。方法 回顾性分析7例经临床及病理检查确诊为肢带型肌营养不良患者的MRI资料,观察双侧大腿肌群脂肪沉积与炎性水肿情况,采用4分法进行评价。并进行统计学分析。结果 肢带型肌营养不良患者大腿肌群MRI均可见脂质沉积和炎性水肿性改变。不同肌肉间脂肪沉积(χ2=75.596,P<0.01)与炎性水肿差异均有统计学意义(χ2=41.368,P<0.01),双侧大腿肌群间脂肪沉积与炎性水肿差异均无统计学意义(P均>0.05)。结论 肢带型肌营养不良患者大腿肌群MRI信号特点及分布具有一定特征,MR检查有助于疾病的诊断。
英文摘要:
      Objective To observe the MRI features of limb-girdle muscular dystrophies. Methods MRI data of 7 patients with limb-girdle muscular dystrophies confirmed by the clinic and muscular biopsy were retrospectively analyzed. Manifestations of fatty deposition and inflammatory edema of the thigh muscles were observed and evaluated with four-points method. Moreover, statistical analysis was performed. Results Both of fatty deposition and inflammatory edema were found in the involved muscles. There were significantly statistical differences of fatty deposition (χ2=75.596, P<0.01) and inflammatory edema (χ2=41.368, P<0.01) among different muscles. No statistical difference of fatty deposition or inflammatory edema was found between left and right thighs (P>0.05). Conclusion There are characteristic MR findings including signal and distribution of the lesions, which are helpful to diagnose limb-girdle muscular dystrophies.
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