| 吴莹,彭鸿灵,赵霞.CEUS诊断卵巢恶性肿瘤的Meta分析[J].中国医学影像技术,2015,31(10):1568~1573 |
| CEUS诊断卵巢恶性肿瘤的Meta分析 |
| CEUS for malignant ovarian tumors: Meta-analysis |
| 投稿时间：2015-03-21 修订日期：2015-07-07 |
| DOI：10.13929/j.1003-3289.2015.10.028 |
| 中文关键词: 超声检查 造影剂 诊断 卵巢肿瘤 Meta分析 |
| 英文关键词:Ultrasonography Contrast media Diagnosis Ovarian neoplasms Meta-analysis |
| 基金项目: |
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| 摘要点击次数: 2741 |
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| 中文摘要: |
| 目的 系统评价CEUS对卵巢恶性肿瘤的诊断价值。方法 系统检索PubMed、Embase、Medline、CBM和CNKI数据库,收集公开发表的关于CEUS诊断卵巢肿瘤的文献资料。采用诊断性实验准确性质量评价工具(QUADAS)评价文献质量。应用Meta-Disc 1.4 软件进行统计分析,得到合并效应量,并绘制汇总受试者工作特征曲线(SROC曲线)。使用Deeks漏斗图评估发表偏倚。结果 共纳入16篇文献,合并的敏感度、特异度和诊断比值比分别为0.89(0.85~0.92)、0.92(0.90~0.94)和103.33(55.79~191.39);SROC曲线下面积为0.97(SE 0.01)。Deeks 漏斗图未见明显发表偏倚。结论 CEUS对卵巢恶性肿瘤具有较高的诊断效能。 |
| 英文摘要: |
| Objective To systematically assess the overall diagnostic performance of CEUS for differentiation of malignant from benign ovarian tumors. Methods PubMed, Embase, Medline, CBM and CNKI databases were systematically searched for relevant articles. Methodological quality of studies was assessed according to the Quality Assessment of Diagnostic Accuracy Studies (QUADAS) tool. Data were pooled to yield summary sensitivity, specificity, diagnostic odds ratio (DOR) and summary receiver operating characteristic (SROC) curve by using Meta-Disc version 1.4 software. Deeks funnel plot was conducted to assess publication bias. Results Sixteen independent studies were enrolled. The pooled statistics of sensitivity, specificity and DOR were 0.89 (0.85—0.92), 0.92 (0.90—0.94) and 103.33 (55.79—191.39), respectively;and the area under the SROC curve was 0.97 (SE 0.01). No publication bias was detected in this meta-analysis. Conclusion CEUS has high diagnostic accuracy in differentiation of malignant from benign ovarian tumors and it may be used preoperatively as a valid diagnostic method in patients suspected of malignant ovarian tumors. |
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