| 杨克柽,王建杰,李卫,李懿.双能CT在增强检查中的应用:体模研究[J].中国医学影像技术,2015,31(9):1410~1413 |
| 双能CT在增强检查中的应用:体模研究 |
| Application of dual-energy CT in contrast enhancement: A phantom study |
| 投稿时间：2015-01-06 修订日期：2015-06-18 |
| DOI：10.13929/j.1003-3289.2015.09.033 |
| 中文关键词: 体层摄影术,X线计算机 双能量 对比剂 体模 |
| 英文关键词:Tomograpy, X-ray computed Dual energy Contrast medium Phantom |
| 基金项目:全军医学科技"十二五"重点课题(BWS11J015). |
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| 中文摘要: |
| 目的 探讨双能CT(DECT)成像技术在增强检查中的应用价值.方法 将浓度不同的碘乙醇溶液和碘水溶液封装于塑料试管中,按顺序固定后浸浴在装满水的截面近似椭圆、周长为86 cm的尼龙复合膜中制成体模原型.于Siemens Somatom Definition Flash扫描仪分别采用常规上腹部条件进行单能和DECT扫描.于专用图像工作站采用Liver VNC软件测量各溶液的碘浓度,并回顾性重建权重为0.5的线性混合图像、最优非线性混合图像(OCM)和CNR最大的单能量图像.结果 两种溶液碘浓度测量值与理论值均呈强相关(r=0.998、0.999,P均 <0.001),但相对误差较大(最大值25.00%).OCM图像和65 keV单能量图像的CNR碘浓度比均显著高于120 kVp图像(P <0.001).结论 DECT可准确区分不同碘溶液的浓度,应用于增强检查可提高图像质量. |
| 英文摘要: |
| Objective To investigate the value of dual-energy CT (DECT) imaging on contrast enhancement. Methods A custom-designed phantom prototype, consisted of 9 tubes of ethanol solutions of different iodine concentrations (0—14 mgI/ml) and 9 tubes of water solutions of different iodine concentrations (1—16 mgI/ml) bathing in a water-filled plastic bag whose cross-section was nearly an ellipse 86 cm in circumference mimicking upper abdomen, was scanned with Siemens Somatom Definition Flash scanner under single-energy mode and DECT mode respectively. Image series were post-processed in a dedicated Siemens Syngo multimodality workplace. Iodine concentrations of different solutions were extracted using Liver VNC. CT data sets obtained at 80/Sn140 kVp were fused using a linear blending method with a weighting factor of 0.5 and a nonlinear blending method with vender-recommended blending window (namely optimum contrast mixed, OCM) respectively. Virtual monochromatic images with maximum CNR were reconstruced based on CNR spectral curve. Results Although the relative error reached a maximum of 25.00%, the iodine concentration measurements of the ethanol and water solutions both showed strong correlation to their nominal values (r=0.998, 0.999, both P <0.001). The reconstructed OCM images and 65 keV monoimages were significantly superior to conventional 120 kVp images in CNR iodine concentration ratio (P <0.001). Conclusion DECT is able to discriminate between iodine concentrations of different solutions precisely and improve contrast medium enhancement substantially. |
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