| 李军,袁美芹,成静,杜婷婷,王甲嘉,芦桂林.二维超声、实时组织弹性成像及声触诊组织量化技术诊断乳腺浸润性导管癌[J].中国医学影像技术,2015,31(8):1234~1237 |
| 二维超声、实时组织弹性成像及声触诊组织量化技术诊断乳腺浸润性导管癌 |
| Two-dimensional ultrasound, real-time tissue ultrasonic elastography and virtual touch tissue quantification in diagnosing breast infiltrative ductal carcinoma |
| 投稿时间：2014-11-27 修订日期：2015-05-02 |
| DOI：10.13929/j.1003-3289.2015.08.030 |
| 中文关键词: 乳腺肿瘤 弹性成像技术 声触诊组织量化 超声检查 |
| 英文关键词:Breast neoplasms Elastic imaging technology Virtual touch tissue quantification Ultrasonography |
| 基金项目: |
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| 摘要点击次数: 3089 |
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| 中文摘要: |
| 目的 探讨二维超声(2D-US)、实时组织弹性成像(UE)及声触诊组织量化(VTQ)技术对乳腺浸润性导管癌(IDC)的诊断价值。方法 对188例患者共213个乳腺病灶术前分别行2D-US、UE及VTQ检查,对各病灶2D-US声像图表现进行超声乳腺影像报告数据系统(BI-RADS-US)分类,UE采用5级评分法判断结节性质,VTQ技术定量测定结节内剪切波速度(SWV)。绘制ROC曲线,比较2D-US、UE、SWV曲线下面积(AUC)。结果 2D-US诊断IDC的敏感度为82.35%(126/153),特异度为71.67%(43/60),准确率为79.34%(169/213)。UE诊断IDC的敏感度为86.27%(132/153),特异度为73.33%(44/60),准确率为82.63%(176/213)。良性及恶性结节的SWV别为(3.09±1.26)m/s、(6.83±2.18)m/s(P<0.05);以3.59 m/s作为诊断恶性病灶的最佳截断值,VTQ诊断IDC的敏感度为86.93%(133/153),特异度为76.67%(46/60),准确率为84.04%(179/213)。2D-US、UE、SWV诊断乳腺IDC的AUC分别为0.811、0.843、0.899,差异有统计学意义(P<0.01)。结论 US、UE及VTQ均有助于鉴别诊断乳腺良性结节及乳腺IDC,UE优于2D-US,VTQ可获得客观的量化指标,重复性好,优于UE和2D-US。 |
| 英文摘要: |
| Objective To investigate the value of two-dimensional ultrasound (2D-US), ultrasonic elastography (UE) and virtual touch tissue quantification (VTQ) in diagnosing breast infiltrative ductal carcinoma (IDC). Methods 2D-US, UE and VTQ were used to examine 188 patients with 213 breast lesions before operation, 2D-US images was classified with breast image reporting and data system-ultrasound, 5-score evaluation was performed in UE, and shear wave velocity (SWV) was determined with VTQ. ROC curve was drown, of area under curve (AUC) of 2D-US, UE and SWV was compared. Results The sensibility, specificity, accuracy of 2D-US for diagnosing IDC was 82.35% (126/153), 71.67% (43/60), 79.34% (169/213), of UE was 86.27% (132/153), 73.33% (44/60), 82.63% (176/213). The SWV of benign lesions and IDC were (3.09±1.26)m/s and (6.83±2.18)m/s (P<0.05). The sensibility, specificity, accuracy was 86.93% (133/153), 76.67% (46/60), 84.04% (179/213) when SWV was 3.59 m/s as cut-off value. AUC of 2D-US, UE, SWV was 0.811, 0.843, 0.899 (P<0.01). Conclusion US, UE and VTQ are helpful in differentiating IDC and benign breast nodules, and UE is better than 2D-US, while VTQ can get objective quantification index and be easy to be repeated, and is superior to UE and 2D-US. |
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