陈胜华,李泉水,熊华花,李振洲,郭国强,邹霞.联合声触诊组织成像技术诊断BI-RADS[J].中国医学影像技术,2015,31(8):1230~1233
联合声触诊组织成像技术诊断BI-RADS
Combination of virtual tough tissue imaging technique in diagnosis of BI-RADS 4 breast lesions
投稿时间:2015-01-28  修订日期:2015-04-09
DOI:10.13929/j.1003-3289.2015.08.029
中文关键词:  乳腺肿瘤  声辐射力触诊成像  乳腺超声影像报告和数据系统
英文关键词:Breast neoplasms  Virtual tough tissue imaging  Breast imaging reporting and data system
基金项目:深圳市科技计划项目(201103114)。
作者单位E-mail
陈胜华 深圳市第二人民医院超声科, 广东 深圳 518035  
李泉水 深圳市第二人民医院超声科, 广东 深圳 518035 李泉水,深圳市第二人民医院超声科,518035。E-mail: liquanshui@126.com 
熊华花 深圳市第二人民医院超声科, 广东 深圳 518035  
李振洲 深圳市第二人民医院超声科, 广东 深圳 518035  
郭国强 深圳市第二人民医院超声科, 广东 深圳 518035  
邹霞 深圳市第二人民医院超声科, 广东 深圳 518035  
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中文摘要:
       目的 评价声触诊组织成像(VTI)在乳腺超声影像报告和数据系统(BI-RADS)4类病变中的诊断价值。方法 选取120例BI-RADS 4类共126个病灶(良性66个,恶性60个),行常规超声检查及VTI。对所有结节分别按照BI-RADS 4类亚分类及VTI标准进行评分,以病理检查结果为金标准,构建ROC曲线,比较BI-RADS 4类亚分类、VTI与联合评分(VTI与BI-RADS 4类亚分类分值相加)对BI-RADS 4类乳腺病灶良恶性的鉴别诊断价值。结果 良、恶性BI-RADS 4类病灶的VTI评分值差异有统计学意义(t=5.72,P<0.05),VTI评分的ROC曲线下面积(AUC)为0.770。以VTI≥4分作为诊断截断点,敏感度、特异度、准确率分别为50.00%(30/60)、90.91%(60/66)、71.43%(90/126)。良、恶性病灶的联合评分值差异有统计学意义(t=6.15,P<0.05),联合评分的AUC为0.806。以联合评分≥6分作为诊断截断点,敏感度、特异度、准确率分别为61.67%(37/60)、93.94%(62/66)、78.57%(99/126)。BI-RADS 4类亚分类的AUC为0.689。联合评分与VTI评分的AUC差异无统计学意义(Z=0.36,P>0.05),但联合评分与BI-RADS 4类亚分类评分的AUC差异有统计学意义(Z=2.60,P<0.05)。结论 VTI在BI-RADS 4类乳腺病灶良、恶性鉴别诊断方面有较高的应用价值,是常规超声的重要辅助诊断技术。
英文摘要:
      Objective To evaluate the diagnostic value of virtual tough tissue imaging (VTI) in breast imaging reporting and data system (BI-RADS) 4 breast lesions. Methods BI-RADS 4 breast lesions (66 benign, 60 malignant) from 120 patients were underwent conventional ultrasonography and VTI. All of lesions were scored in accordance with BI RADS 4 level subclassification and VTI criteria. The diagnostic performances of VTI score and the combined score (VTI and BI-RADS 4 level subclassification) were evaluated with ROC curve based on the pathological results. The diagnostic value of the two different methods was evaluated. Results The VTI score difference between the benign and malignant breast lesions was statistically significant (t=5.72, P<0.05), the area under the ROC curve (AUC) of VTI was 0.770. VTI score ≥4 as the point of diagnosis benign and malignant lesions, the sensitivity, specificity and accuracy was 50.00% (30/60), 90.91% (60/66) and 71.43% (90/126), respectively. There was significant difference between the benign and malignant breast lesions in the combined score (t=6.15, P<0.05), the AUC was 0.806. The combined score ≥6 as a diagnostic cut-off point, the sensitivity, specificity and accuracy was 61.67% (37/60), 93.94% (62/66) and 78.57% (99/126) respectively. The AUC of subclassification was 0.689. AUC had no significant difference between the VTI score and the combined score (Z=0.36, P>0.05), but there was significant statistical difference of AUC between the combined and subclassification score (Z=2.60, P<0.05). Conclusion VTI has significant value for differential diagnosis of benign and malignant breast lesions of BI-RADS 4 level, which is a useful complementary for conventional ultrasonography.
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