| 蔡自强,尤克增,柴仕红,闫培华,赵世超.3.0T磁共振扩散加权成像ADC值在浸润性乳腺癌分级中的应用[J].中国医学影像技术,2015,31(7):1041~1044 |
| 3.0T磁共振扩散加权成像ADC值在浸润性乳腺癌分级中的应用 |
| Application of ADC values of diffusion-weighted imaging on 3.0T MRI in classification of invasive breast cancer |
| 投稿时间：2014-12-06 修订日期：2015-05-04 |
| DOI：10.13929/j.1003-3289.2015.07.021 |
| 中文关键词: 乳腺肿瘤 扩散磁共振成像 表观扩散系数 |
| 英文关键词:Breast neoplasms Diffusion magnetic resonance imaging Apparent diffusion coefficient |
| 基金项目: |
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| 摘要点击次数: 2015 |
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| 中文摘要: |
| 目的 探讨扩散加权成像ADC值在评估浸润性乳腺癌肿瘤分级中的应用价值。方法 选取经手术后病理学确诊的浸润性乳腺癌患者81例,术前均采用具备双边、四通道乳腺线圈的3.0T MR行DWI,分析浸润性乳腺癌的肿瘤分级、组织学与ADC值的关系。结果 81例患者中,共检出101个恶性病灶,DWI检测到恶性病灶99个,检出率为98.02%(99/101)。肿瘤Ⅰ、Ⅱ、Ⅲ级的ADC值分别为(1.12±0.19)×10-3 mm2/s、(1.02±0.16)×10-3 mm2/s、(0.89±0.15)×10-3 mm2/s,三者差异有统计学意义(F=19.078,P<0.001)。ADC值与肿瘤分级呈负相关(r=-0.450,P<0.01)。结论 ADC值与浸润性乳腺癌的肿瘤分级具有相关性,可用于评估其恶性程度。 |
| 英文摘要: |
| Objective To explore the application of ADC values of DWI in the classification of invasive breast cancer. Methods Eighty-one patients whith invasive breast cancer proved by pathology after surgery were DWI before surgery by 3.0T MR with four-channel bilateral breast coil. The relations between the tumor grades, histology and ADC values of invasive breast cancer were analyzed. Results In 81 cases, 101 malignant lesions were detected. 99 malignant lesions were detected by DWI, detectable rate was 98.02% (99/101). The ADC values of grade Ⅰ, Ⅱ, Ⅲ tumors were (1.12±0.19)×10-3 mm2/s, (1.02±0.16)×10-3 mm2/s, (0.89±0.15)×10-3 mm2/s, respectively. The differences among the three grades were statistically significant (F=19.078, P<0.001). There was a negative correlation between ADC values and tumor grades (r=-0.450, P<0.01). Conclusion There is correlation between ADC values and tumor grades, which can be used to evaluate the malignancy. |
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