| 李雪,王学梅,黄崑,姜镔.剪切波弹性成像评估原发性肝细胞癌手术范围[J].中国医学影像技术,2015,31(5):750~753 |
| 剪切波弹性成像评估原发性肝细胞癌手术范围 |
| Shear wave elasticity imaging in evaluation of operation range of hepatocellular carcinoma |
| 投稿时间：2014-08-17 修订日期：2015-01-20 |
| DOI：10.13929/j.1003-3289.2015.05.028 |
| 中文关键词: 弹性成像技术 癌,肝细胞 手术范围 |
| 英文关键词:Elasticity imaging techniques Carcinoma, hepatocellular Surgical margin |
| 基金项目: |
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| 摘要点击次数: 3381 |
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| 中文摘要: |
| 目的 探讨实时剪切波弹性成像(SWE)技术在原发性肝细胞癌(HCC)手术范围评估中的临床应用价值。方法 回顾性分析45例经术后病理检查证实为HCC患者的SWE声像图资料。对比HCC病灶,距病灶1、2、3 cm肝组织及正常肝组织的弹性模量值,并进行统计学分析。结果 HCC病灶,距病灶1、2、3 cm肝组织及正常肝组织弹性模量的平均值分别为(28.19±6.14)kPa、(17.14±5.34)kPa、(13.44±3.76)kPa、(10.98±3.44)kPa及(10.03±3.69)kPa。HCC病灶,距病灶1、2 cm肝组织与距病灶3 cm肝组织及正常肝组织间差异均有统计学意义(P 均<0.05);距病灶1 cm肝组织与距病灶2 cm肝组织间差异有统计学意义(P<0.05);距病灶3 cm肝组织与正常组织间差异无统计学意义(P >0.05)。2名医师对HCC病灶,距病灶1、3 cm肝组织及正常肝组织所测弹性模量值差异均无统计学意义(P均>0.05),仅对距病灶2 cm肝组织弹性模量值差异有统计学意义(P=0.02)。结论 采用SWE技术测定HCC病灶及其周边不同范围肝组织的弹性模量值可为术前评估手术切缘范围提供参考信息。 |
| 英文摘要: |
| Objective To investigate the clinical significance of the shear-wave elastography in the surgical margin of HCC. Methods SWE ultrasonogram of 45 patients historically confirmed HCC was retrospectively analyzed, and then statistical analysis was performed based on the comparision of the elastic modulus value (mean value) of HCC lesions, peripherd tissue (distance from the lesion was 1 cm, 2 cm and 3 cm respectively) and the normal liver tissue. Results The mean elasticity value of HCC lesions, peripheral 1 cm, 2 cm, 3 cm and normal liver tissue were (28.19±6.14)kPa, (17.14±5.34)kPa, (13.44±3.76) kPa, (10.98±3.44)kPa and (10.03±3.69)kPa respectively. The elastic modulus of HCC lesions and peripheral 1 cm and 2 cm were significantly higher than those of normal liver tissue and peripheral 3 cm (P<0.05). The difference between peripheral 1 cm and peripheral 2 cm showed statistical significance (P<0.05). However, there was no significant difference between peripheral 3 cm and the normal liver tissue (P>0.05). The difference between the elastic modulus of the two physicicans including HCC lesions, peripheral 1 cm, 3 cm and normal liver tissue were not significant (P>0.05) exclusive of the peripheral 2 cm group (P=0.02). Conclusion Real-time SWE may provide theoretical support for surgical margin of HCC by determining the elastic modulus value of hepatocellular cancer and its peripheral tissue. |
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