| 丁重阳,孙晋,吴宇霖,李洋洋,杨伟,李天女.治疗前18F-FDG PET/CT最大标准摄取值评估鼻腔NK/T细胞淋巴瘤的预后[J].中国医学影像技术,2015,31(5):729~732 |
| 治疗前18F-FDG PET/CT最大标准摄取值评估鼻腔NK/T细胞淋巴瘤的预后 |
| Maximum standard uptake on pretreatment 18F-FDG PET/CT scan in assessment of prognosis of nasal natural killer/T-cell lymphoma |
| 投稿时间：2014-09-09 修订日期：2015-03-12 |
| DOI：10.13929/j.1003-3289.2015.05.023 |
| 中文关键词: 鼻肿瘤 淋巴瘤,非霍奇金 18F氟脱氧葡萄糖 预后 |
| 英文关键词:Nose neoplasms Lymphoma, non-Hodgkin Fluorodeoxyglucose F18 Prognosis |
| 基金项目:放射性靶向治疗乳腺癌及骨转移的研究(201303038)。 |
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| 中文摘要: |
| 目的 探讨18F-FDG PET/CT最大标准摄取值(SUVmax)评估治疗前鼻腔NK/T细胞淋巴瘤患者预后的价值。方法 31例确诊的鼻腔NK/T细胞淋巴瘤患者均于治疗前接受18F-FDG PET/CT检查,患者预后单因素分析采用Kaplan-Meier法,采用Cox模型进行多因素分析。结果 31例鼻腔NK/T细胞淋巴瘤患者治疗前18F-FDG PET/CT显像中位SUVmax为12.7(4.4~25.7)。单因素分析结果显示,B症状、KPI、治疗模式、SUVmax与鼻腔NK/T 细胞淋巴瘤患者的预后相关(P均<0.05);多因素分析显示仅有SUVmax是影响患者预后的独立危险因素(P=0.018)。结论 鼻腔NK/T细胞淋巴瘤患者治疗前18F-FDG PET/CT的SUVmax能够预测患者的预后。 |
| 英文摘要: |
| Objective To explore the prognostic value of maximum standard uptake (SUVmax) of 18F-FDG PET/CT in assessment of prognosis of newly diagnosed nasal natural killer (NK)/T cell lymphoma patients on pretreatment. Methods The clinical data of 31 patients with nasal NK/T cell lymphoma undergoing 18F-FDG PET/CT scan at pretreatment were analyzed retrospectively. The prognostic factors were analyzed with univariate and multivariate analysis. Results In 31 patients, the median SUVmax on pretreatment 18F-FDG PET/CT was 12.7 (4.4—25.7). In univariate analysis, B symptoms, KPI, treatment mode and SUVmax were found to be the prognostic factors (all P<0.05). Multivariate analysis indicated that only SUVmax was the independent unfavorable prognostic factor (P=0.018). Conclusion The SUVmax on pretreatment 18F-FDG PET/CT scan in nasal NK/T cell lymphoma patients can be used to predict the patients prognosis. |
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