| 梁心红,余林,孙戈,陈德基.320排容积CT低管电压结合低浓度对比剂冠状动脉成像与冠状动脉造影的对比研究[J].中国医学影像技术,2015,31(3):458~462 |
| 320排容积CT低管电压结合低浓度对比剂冠状动脉成像与冠状动脉造影的对比研究 |
| Comparative study of combined low tube potential and low contrast medium dose 320-slice coronary CT angiography with invasive coronary angiography |
| 投稿时间：2014-09-25 修订日期：2015-01-14 |
| DOI：10.13929/j.1003-3289.2015.03.039 |
| 中文关键词: 冠状动脉 体层摄影术,X线计算机 血管造影术 碘摄入量 辐射剂量 |
| 英文关键词:Coronary artery Tomography, X-ray computed Angiography Iodine dose Radiation dose |
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| 中文摘要: |
| 目的 探讨320排容积CT冠状动脉CTA低管电压、低浓度对比剂扫描的可行性。方法 前瞻性分析54例临床疑似冠状动脉粥样硬化性心脏病患者的CCTA检查结果,并与经导管冠状动脉造影术(CCA)结果进行对照。CCTA采用100 kV管电压,对比剂采用270 mgI/ml的碘克沙醇。结果 CCTA显示冠状动脉中度以上狭窄(≥50%)及重度狭窄(≥75%)的敏感度、特异度、阳性预测值、阴性预测值、正确指数及符合率分别为89.55%、96.08%、78.95%、98.25%、85.63%、96.84%及92.68%、97.24%、76.00%、99.29%、89.92%、95.16%。CCTA与CCA在显示冠状动脉狭窄程度方面的一致性良(Kappa=0.752,P<0.001)。CCTA诊断冠状动脉中度以上狭窄(≥50%)的ROC曲线下面积为0.930。结论 应用320排容积CT行CCTA低管电压、低浓度对比剂扫描诊断冠状动脉狭窄具有可行性。 |
| 英文摘要: |
| Objective To explore the feasibility of a low tube voltage setting for 320-slice volume coronary CT angiography (CCTA) using a low-dose contrast medium protocol. Methods Fifty-four patients suspected of coronary heart disease underwent 320-slice CTA. The results of CTA was compared with those of catheter coronary angiography (CCA). The protocol of CCTA was scanned using 100 kVp and Iodixanol (270 mgI/ml). Results The sensitivity, specificity, positive and negative predictive value, correct indices and accordance rate of CCTA was 89.55%, 96.08%, 78.95%, 98.25%, 85.63% and 96.84% in showing moderate and severe stenosis (≥50%), while that was 92.68%, 97.24%, 76.00%, 99.29%, 89.92% and 95.16% respectively, in showing severe stenosis (≥75%). It had a good consistency in evaluating the stenosis degree of coronary artery between CCTA and CCA (Kappa=0.752, P<0.001). The area under curve of ROC of CCTA in dignosis of moderate and severe stenosis (≥50%) was 0.930. Conclusion A low tube voltage setting for 320-slice volume CCTA using a low-dose contrast medium protocol has the feasibility in diagnosis of narrow degree of coronary artery. |
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