| 张敏,李建奇,赵小虎,裴孟超,王培军.头部位移对纵向研究波谱结果可重复性的影响[J].中国医学影像技术,2015,31(1):132~136 |
| 头部位移对纵向研究波谱结果可重复性的影响 |
| Effect of head displacement on the reproducibility of MRS in longitudinal research |
| 投稿时间：2014-04-09 修订日期：2014-08-16 |
| DOI：10.13929/j.1003-3289.2015.01.038 |
| 中文关键词: 磁共振波谱学 头部 可重复性结果 位移 |
| 英文关键词:Magnetic resonance spectroscopy Head Reproducibility of results Translocation |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨不同形式位移经校正后对MRS结果可重复性的影响。方法 纳入20名被试者于无位移、平动位移、平动-转动位移时分别进行MRS扫描,每次间隔10 min,位移状态扫描前由SPM软件自动获取VOI位置,测量并比较平动位移、平动-转动位移经校正后VOI内N-乙酰天门冬氨酸(NAA)、肌酸(Cr)、磷酸肌酸(PCr)和胆碱复合物(Cho)含量及NAA/(Cr+PCr)和Cho/(Cr+PCr);计算上述参数位移对比无位移时差异性系数(CV)和重复性指数(RI)。结果 平动位移经校正后各参数与无位移间差异均无统计学意义(P均>0.05),平动-转动位移经校正后除Cr外,NAA、Cho、NAA/Cr+PCr、Cho/Cr+PCr与无位移间差异均有统计学意义(P均<0.01)。平动位移和平动-转动位移经校正后与无位移时比较,NAA、Cho、Cr含量及NAA/(Cr+PCr)、Cho/(Cr+PCr)的平均CV均<12%,重复性可接受;RI值除Cr外,余参数均<20%,重复性可接受。结论 MRS中对患者头部平动位移可准确校正,所得结果重复性较好。 |
| 英文摘要: |
| Objective To determine the effect of different displacement on reproducibility of MRS scanning results. Methods Twenty healthy volunteers were enrolled and underwent MRS scanning under non-displacement, translation displacement and translation-rotation displacement, respectively, given a ten-minute rest between each two examinations. The VOI before displacement was corrected by automatic repositioning method using software SPM. The N-acetyl aspartate (NAA), creatine (Cr), phosphocreatine (PCr), choline-containing compounds (Cho), and NAA/(Cr+PCr) and Cho/(Cr+PCr) were measured and compared among each way of displacement. The variance coefficient (CV) and the repeatability index (RI) of each parameter for each displacement compared to non-displacement were calculated. Results No significant differences of above parameters were showed between adjusted translation displacement and non-displacement group (all P>0.05), while significant differences of NAA, Cho, NAA/(Cr+PCr), Cho/(Cr+PCr) were found between adjusted translation-rotation displacement and non-displacement group (all P<0.01), but not Cr. The CV of above metabolites and ratio between adjusted displacement and non-displacement were all <12%, meaning acceptable repeatability. The RI of above metabolites and ratio between adjusted displacement and non-displacement were all <20% excluding Cr, also meaning acceptable repeatability. Conclusion In MRS, translation of subject's head position can be accurately adjusted with good repeatable results. |
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