| 顾胜利,陈亚青,蒋珺,徐依耑,管雯斌.三维彩色血管能量成像评估乳腺癌预后[J].中国医学影像技术,2014,30(10):1523~1526 |
| 三维彩色血管能量成像评估乳腺癌预后 |
| Three-dimensional color power angiography in assessment of prognosis in breast cancer |
| 投稿时间：2014-05-15 修订日期：2014-08-01 |
| DOI： |
| 中文关键词: 乳腺肿瘤 超声检查, 多普勒 成像, 三维 预后 |
| 英文关键词:Breast neoplasms Ultrasonography, Doppler Imaging, three-dimensional Prognosis |
| 基金项目:上海交通大学医工交叉研究基金项目（YG2009MS05）、上海市科委重点项目（064119632）。 |
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| 中文摘要: |
| 目的 探讨三维彩色血管能量成像（3D-CPA）评估乳腺浸润性导管癌预后的价值。方法 回顾分析82例手术病理证实的浸润性导管癌患者的3D-CPA资料，获取并比较预后相关指标不同的肿瘤间3D-CPA参数，包括肿瘤内血管指数（VI）、血流指数（FI）和血管-血流指数（VFI）差异。结果 直径>2 cm、病理Ⅲ级、伴腋窝淋巴结转移、孕激素受体（PR）表达阴性肿瘤，其VI值高于直径≤2 cm、病理Ⅱ级、无腋窝淋巴结转移和PR表达阳性肿瘤（P均<0.05）；直径>2 cm、雌激素受体（ER）表达阴性肿瘤FI值高于直径≤2 cm、ER表达阳性肿瘤（P均<0.05）；直径>2 cm、病理Ⅲ级、PR表达阴性肿瘤VFI值高于直径≤2 cm、病理Ⅱ级和PR表达阳性肿瘤（P均<0.05）；而不同人表皮生长因子-2表达肿瘤间VI、FI和VFI值差异无统计学意义（P均>0.05）。结论 预后相关指标不同的乳腺癌3D-CPA参数存在差异，对预测预后具有潜在的临床应用价值。 |
| 英文摘要: |
| Objective To investigate the value of three-dimensional color power angiography (3D-CPA) in assessment of prognosis in invasive ductal carcinoma of breast. Methods 3D-CPA data of 82 patients with invasive ductal carcinoma confirmed by pathology were retrospectively analyzed. 3D-CPA parameters, including vascularization index (VI), flow index (FI) and vascularization-flow index (VFI) were obtained and compared between tumors with different prognosis related factors. Results The tumors with diameter >2 cm, grade Ⅲ, metastasis of the lymph node and negative expression of progesterone receptor (PR) showed higher VI compared with tumors with diameter ≤2 cm, grade Ⅱ, non-metastasis of the lymph node and positive expression of PR (all P<0.05). The tumors with diameter >2 cm and negative expression of estrogen receptor (ER) showed higher FI compared with tumors with diameter ≤2 cm and positive expression of ER (both P<0.05). The tumors with diameter >2 cm, grade Ⅲ and negative expression of PR showed higher VFI compared with tumors diameter ≤2 cm, grade Ⅱ and positive expression of PR (all P<0.05). Tumors with different expression of human epidermal growth factor receptor 2 had no significant differences in VI, FI and VFI (all P>0.05). Conclusion In breast cancer, parameters of 3D-CPA have differences among tumors with different prognosis related factors, which is of use in predicting the prognosis. |
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