| 张娅,陈建宇,钟镜联,付佳,朱洪蕾,许耀东,区永康.磁共振增强3D-FLAIR序列诊断耳眩晕患者内耳内淋巴积水[J].中国医学影像技术,2014,30(8):1183~1187 |
| 磁共振增强3D-FLAIR序列诊断耳眩晕患者内耳内淋巴积水 |
| Diagnosis of endolymphatic hydrops using contrast-enhanced MRI 3D-FlAIR sequence |
| 投稿时间：2014-04-04 修订日期：2014-07-02 |
| DOI： |
| 中文关键词: 耳眩晕 内淋巴积水 磁共振成像 液体衰减反转恢复序列 |
| 英文关键词:Meniere’s Disease Endolymphatic hydrops Magnetic resonance imaging Fluid attenuated inversion recovery sequence |
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| 中文摘要: |
| 目的 探讨MRI增强3D-FLAIR序列显示耳眩晕（MD）内耳内淋巴积水的价值。方法 在34例患者中筛选57耳，分为MD组、可疑MD组、其他疾病组及正常组。对每耳经咽鼓管咽口注射稀释的马根维显注射液1 ml，24 h后行3D-FLAIR序列扫描。测量并比较各组内淋巴积水的差异；计算该影像方法诊断（可疑）MD的敏感度、特异度。结果 4组平均前庭内淋巴间隙面积的百分比差异有统计学意义（P<0.05）。除MD组与可疑MD组、其他疾病组与正常组外，其他组间两两比较差异均有统计学意义（P均<0.05）。4组间内淋巴积水分级存在差异（P<0.05）；其中MD组与其他疾病组、MD组与正常组、可疑MD组与正常组差异有统计学意义（P均<0.0083）。MRI增强3D-FLAIR序列诊断（可疑）MD的敏感度为77.42%、特异度为80.77%；影像诊断方法与单纯临床诊断（可疑）MD存在相关性（r=0.50）。结论 MRI增强3D-FLAIR能直观显示内耳内淋巴积水及积水程度，是诊断MD、特别是可疑MD的有效影像学方法。 |
| 英文摘要: |
| Objective To investigate the value of contrast 3D-FLAIR in diagnosing endolymphatic hydrops (EH) in Meniere's Disease (MD). Methods Total recruited 57 ears were divided into four groups: MD group, probable MD group, other diseases group and normal group. Axial 3D-FLAIR scans were performed after administration of Gd-DTPA 1 ml of diluted 8-fold with saline via pharyngeal opening of auditory tube with a delay of 24 h. The area ratio of endolymphatic space to total fluid space and EH grade were compared. The sensitivity, specificity of contrast 3D-FLAIR sequence was calculated. Results Statistical differences in average area ratio of endolymphatic space to total fluid space were found (P<0.05). Differences had statistially significance except between the groups of MD and probable MD, other diseases and normal (P<0.05). Statistical differences of EH grade were found among four groups (P<0.05). Signiciant differences were found between the groups of MD and other diseases, MD and normal, probable MD and normal (all, P<0.0083). The sensitivity, specificity of contrast 3D-FLAIR sequence was 77.42%, 80.77% independently. Imaging diagnosis and clinical diagnosis had correlation in diagnosis of (probable) MD (r=0.50). Conclusion MRI contrast 3D-FLAIR sequence not only reveals endolymphatic hydrops, but also identifies the grade of endolymphatic hydrops. Accordingly, MRI 3D-FLAIR sequence has general application in diagnosing (probable) MD. |
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