| 李淑健,程敬亮,张勇,孙梦恬.DWI及动态增强MRI鉴别诊断舌良恶性病变[J].中国医学影像技术,2014,30(8):1179~1182 |
| DWI及动态增强MRI鉴别诊断舌良恶性病变 |
| DWI and dynamic contrast-enhanced MRI in differentially diagnosing benign and malignant lesions of the tongue |
| 投稿时间：2014-04-01 修订日期：2014-04-16 |
| DOI： |
| 中文关键词: 舌肿瘤 磁共振成像 扩散磁共振成像 诊断 鉴别 |
| 英文关键词:Tongue neoplasms Magnetic resonance imaging Diffusion magnetic resonance imaging Diagnosis differential |
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| 中文摘要: |
| 目的 评价DWI及动态增强MRI鉴别诊断舌良恶性病变的价值。方法 对75例经病理确诊的舌部病变患者行DWI和动态增强MRI。测量并比较舌良恶性病变病灶ADC值，绘制ROC曲线分析ADC值诊断舌恶性肿瘤效能；比较舌良恶性病变时间-信号强度曲线（TIC）分型差异。结果 舌恶性病变的ADC值[（1.12±0.21）×10-3mm2/s]明显低于良性病变[（1.84±0.47）×10-3mm2/s，P<0.001）；以ADC值1.30×10-3mm2/s为阈值，诊断舌恶性病变的敏感度、特异度和准确率分别为90.70%、93.75%和92.00%，ROC曲线下面积为0.957。良性病变（除外8例囊肿）中19例（19/24，79.17%）TIC为Ⅲ型，5例（5/24，20.83%）为Ⅱ型；恶性病变中39例（39/43，90.70%）TIC为Ⅰ型，4例（4/43，9.30%）为Ⅱ型。结论 舌良恶性病变DWI和动态增强MRI具有不同特征，ADC值和TIC曲线有助于鉴别诊断两者。 |
| 英文摘要: |
| Objective To assess the value of DWI and dynamic contrast-enhanced MRI in differentially diagnosing benign and malignant lesions of the tongue. Methods Totally 75 patients of lingual lesions confirmed by pathology underwent DWI and dynamic contrast-enhanced MRI. The ADC values of benign and malignant lesions of the tongue were measured and compared. ROC curve was drawn to analyze the ability of ADC in diagnosing lingual malignant tumor. The time-intensity curve (TIC) type was analyzed and compared between benign and malignant lesions. Results The ADC of malignant tumors ([1.12±0.21]×10-3 mm2/s) was significantly lower than that of benign lesions ([1.84±0.47]×10-3 mm2/s, P<0.05). Taking 1.30×10-3 mm2/s as cut-off value for diagnosing malignant tumor, the sensitivity, specificity and accuracy was 90.70%, 93.75% and 92.00% and the area under ROC curve was 0.957. In patients with benign lesions (excluding 8 cases of cyst) there were 19 (19/24, 79.17%) with type Ⅲ and 5 (5/24, 20.83%) with typeⅡ TIC. In patients with malignant tumors there were 39 (39/43, 90.70%) with typeⅠand 4 (4/43, 9.30%) with typeⅡ TIC. Conclusion Benign and malignant lesion of the tongue has different features in DWl and dynamic contrast-enhanced MRI, respectively, which is helpful for differential dignosis of them. |
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