| 李丽雅,吕国荣,李敏,凌乐文.产前超声建立胎儿甲状腺正常参考值[J].中国医学影像技术,2014,30(6):897~900 |
| 产前超声建立胎儿甲状腺正常参考值 |
| Establishment reference ranges of normal developing fetal thyroid with two-dimensional and three-dimensional ultrasound |
| 投稿时间：2013-12-11 修订日期：2014-04-01 |
| DOI： |
| 中文关键词: 甲状腺 胎儿 超声检查,产前 |
| 英文关键词:Thyroid Fetus Ultrasonography,prenatal |
| 基金项目:2012年泉州市科技局第二批指导性科技计划项目（16）、福建医科大学附属第二医院苗圃科研基金（MP56）。 |
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| 中文摘要: |
| 目的 利用超声观察胎儿甲状腺大小与孕周（GA）的关系，建立胎儿发育过程中甲状腺大小的正常参考值范围。方法 应用二维及三维超声计算机辅助虚拟脏器分析技术测量306胎胎龄20~40周正常单胎胎儿甲状腺长径、前后径、横径、周长、面积、体积，并分析各测量值与GA的关系。结果 超声声像图中，胎儿甲状腺呈中等回声，甲状腺大小随GA增加而增大，其与GA的回归方程分别为：长径=0.059GA+0.055（r=0.813，P<0.05），前后径=0.025GA+0.16（r=0.747，P<0.05），横径=0.036GA+0.275（r=0.752，P<0.05），周长=0.159GA-0.135（r=0.744，P<0.05），面积=0.045GA-0.358（r=0.689，P<0.05），体积=0.067GA-1.083（r=0.755，P<0.05）。同一医师和不同医师测量甲状腺大小的重复性均较高，且不同医师测量甲状腺大小的一致性较好。结论 产前超声建立胎儿甲状腺大小的正常参考值范围，有助于评估其发育情况及早期诊断甲状腺异常。 |
| 英文摘要: |
| Objective To observe the relationship between fetal thyroid size and gestational age (GA), and to establish the reference ranges of normal developing fetal thyroid. Methods Fetal thyroid size, including fetal thyroid long diameter, antero-posterior diameter, transverse diameter, circumference, area and volume were measured in 306 normal single fetuses with 20—40 GA with two-dimensional ultrasonography (2DUS) and three-dimensional ultrasonography virtual organ computer-aided analysis (3DUS-VOCAL) technology. The correlation between fetal thyroid size and GA were analyzed. Results Fetal thyroid appeared as medium echogenicity in prenatal ultrasound, and the size of fetal thyroid was strongly correlated with GA. The regression equations were as follows: Long diameter=0.059GA+0.055 (r=0.813, P<0.05), antero-posterior diameter=0.025GA+0.16 (r=0.747, P<0.05), transverse diameter=0.036GA+0.275 (r=0.752, P<0.05), circumference=0.159GA-0.135 (r=0.744, P<0.05), area=0.045GA-0.358 (r=0.689, P<0.05), volume=0.067GA-1.083 (r=0.755, P<0.05). Either intraobserver or interobserver repeatability of the obtained fetal thyroid sizes were good, so as the interobserver consistency. Conclusion The normal reference ranges of fetal thyroid size in different GA are useful in assessment of fetal thyroid development and the early diagnosis of fetal thyroid dysfunction. |
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