| 吴大勇,张文艳,陈江红,边艳珠.肺灌注SPECT/CT评估肺栓塞治疗效果[J].中国医学影像技术,2014,30(4):540~543 |
| 肺灌注SPECT/CT评估肺栓塞治疗效果 |
| Pulmonary perfusion SPECT/CT in evaluation on therapeutic effect of pulmonary embolism |
| 投稿时间：2013-10-28 修订日期：2014-02-20 |
| DOI： |
| 中文关键词: 肺栓塞 体层摄影术,发射型计算机,单光子 灌注成像 溶栓治疗 |
| 英文关键词:Pulmonary embolism Tomography, emission-computer, single-photon Perfusion imaging Thrombolysis treatment |
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| 中文摘要: |
| 目的 观察应用肺灌注SPECT/CT评估肺栓塞（PE）治疗效果的价值。方法 回顾性分析经肺灌注SPECT/CT显像诊断为PE后接受溶栓及抗凝治疗的107例患者，按病程将其分为<7天组（n=37）、7~14 天组（n=45）和>14天组（n=25），均于溶栓治疗后7天内再次接受肺灌注SPECT/CT显像。记录各组溶栓治疗后血流灌注改善的肺段数，计算肺段血流灌注改善率，并对3组进行比较。结果 溶栓治疗前，肺灌注SPECT/CT共于107例患者中检出646个栓塞肺段 （646/1926，33.54%）；治疗后，360个（360/646，55.73%）肺段血流灌注改善，未发现新的栓塞肺段。<7天组、7~14天组及>14天组肺段血流灌注改善率分别为74.21%（164/221）、58.05%（155/267）和25.95%（41/158），3组差异有统计学意义（χ2=87.97，P<0.05），其中<7天组与7~14 天组差异亦有统计学意义（χ2=13.94，P<0.05）。结论 肺灌注SPECT/CT显像可用于评价溶栓治疗PE的效果。 |
| 英文摘要: |
| Objective To observe the value of pulmonary perfusion SPECT/CT in evaluation on therapeutic effect of pulmonary embolism (PE). Methods Totally 107 PE patients diagnosed with pulmonary perfusion SPECT/CT were retrospectively analyzed. All patients underwent thrombolytic and anticoagulant therapy, and then pulmonary perfusion SPECT/CT was rechecked within 7 days. According to course of disease, the patients were divided into 3 groups, i.e. <7 days group (n=37), 7-14 days group (n=45) and >14 days group (n=25). The number of improved pulmonary segments after thrombolysis treatment were recorded, and then the percentage that the number of reperfusion pulmonary segments to the total number of embolized segments before thrombolysis were calculated and compared statistically. Results Before thrombolysis treatment, a total of 646 (646/1926, 33.54%) embolized pulmonary segments were detected. After thrombolysis treatment, improvement was observed in 360 (360/646, 55.73%) segments, while no newly developed embolized segments was found. The percentage of improved pulmonary segments in <7 days group, 7-14 days group and >14 days group was 74.21% (164/221), 58.05% (155/267) and 25.95% (41/158), respectively. Significant differences were found among 3 groups (χ2=87.97, P<0.05), as well as between <7 days group and 7-14 days group (χ2=13.94, P<0.05). Conclusion Pulmonary perfusion SPECT/CT imaging can be used to evaluate therapeutic effect of pulmonary embolism. |
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