| 侯利芳,郑敏,王玲,李硕,郝彩芳.QAS及X-strain技术评价系统性红斑狼疮患者颈动脉弹性[J].中国医学影像技术,2014,30(3):386~389 |
| QAS及X-strain技术评价系统性红斑狼疮患者颈动脉弹性 |
| Evaluation on elasticity of carotid artery with QAS and X-strain technique in patients with systemic lupus erythematosus |
| 投稿时间：2013-09-05 修订日期：2014-01-06 |
| DOI： |
| 中文关键词: 红斑狼疮,系统性 颈动脉 超声检查 |
| 英文关键词:Lupus erythematosus, systemic Carotid artery Ultrasonography |
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| 中文摘要: |
| 目的 应用血管硬度检测（QAS）技术及应变和应变率成像（X-strain）技术定量评价系统性红斑狼疮（SLE）患者颈动脉弹性。方法 根据病史将77例SLE患者分为SLE 1组（病史<5年，46例）和SLE 2组（病史≥5年，31例），另选取40名健康志愿者作为对照组。采用常规超声、QAS技术和X-strain技术检测双侧颈动脉，比较各组间常规超声参数、QAS技术和X-strain技术参数差异，分析各参数间的相关性。结果 SLE 1组与对照组内-中膜厚度（IMT）、弹性系数α、弹性系数β、脉搏波速度和动脉反射波增强指数差异无统计学意义（P均>0.05），SLE 2组上述参数与对照组和SLE 1组相比明显增高（P均<0.05）；3组间最大圆周应变及圆周应变率比较差异均有统计学意义（P均<0.05），且随病程延长逐渐减低；颈动脉IMT与QAS参数、X-strain参数之间具有明显相关性。结论 应用QAS和X-strain技术能早期检测SLE患者颈动脉弹性功能改变，对预防和干预SLE患者心血管事件非常重要。 |
| 英文摘要: |
| Objective To observe the value of quantitative arterial stiffness (QAS) and X-strain technique in assessment of changes for carotid artery elasticity in patients with systemic lupus erythematosus (SLE). Methods Seventy-seven patients with SLE were divided into SLE 1 group (duration<5 years, n=46) and SLE 2 group (duration≥5 years, n=31) . Forty healthy volunteers were enrolled as control group. Ultrasound, QAS and X-strain techique were performed to evaluate carotid arterial elastic function, and the parameters were compared among groups. Correlation of these parameters was analyzed. Results There was no difference of intima-media thickness (IMT), elastic coefficient α, elastic coefficient β, pulse wave velocity nor augmentation index between control group and SLE 1 group (all P>0.05). The above parameters of SLE 2 group significantly increased compared with control group and SLE 1 group (all P<0.05). The maximum value of circumferential strain and circumferential strain rate were significantly different among three groups (all P<0.05), which decreased along with the course. IMT, QAS parameters and X-strain parameters were significantly correlated each other. Conclusion QAS and X-strain technology can early detect changes of carotid arterial elasticity in SLE patients, which are important for prevention and intervention of cardiovascular events for SLE patients. |
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