| 曲鑫鑫,孙洪赞,朱文珍,卢再鸣*.DWI联合动脉自旋标记及MRA评价脑梗死缺血半暗带[J].中国医学影像技术,2014,30(1):11~15 |
| DWI联合动脉自旋标记及MRA评价脑梗死缺血半暗带 |
| Pulsed arterial spin-labeling combined with DWI and MRA for evaluation of ischemic penumbra |
| 投稿时间：2013-07-08 修订日期：2013-10-22 |
| DOI： |
| 中文关键词: 动脉自旋标记 扩散磁共振成像 缺血半暗带 |
| 英文关键词:Arterial spin labeling Diffusion magnetic resonance imaging Ischemic penumbra |
| 基金项目:国家“十二五”科技支撑计划课题项目（2011BAI08B10）。 |
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| 中文摘要: |
| 目的 观察DWI联合动脉自旋标记（ASL）、MRA评价急性脑梗死缺血半暗带（IP）的价值。方法 对40例发病时间在24 h内的急性脑梗死患者行常规MR、MRA、DWI及ASL检查，根据ASL灌注异常区面积与DWI信号异常区面积分为ASL>DWI组、ASL≈DWI组、ASL结果 ASL>DWI组（即IP患者）25例（25/40，62.50%），血管狭窄程度以0、1级为主；其病灶中心ADC值和rCBF信号强度值与IP区及健侧相比均显著下降（P<0.001），IP区ADC值与健侧相比未见明显下降（P=0.59），而rCBF较健侧下降明显（P<0.001）。ASL≈DWI组2例（2/40，5.00%），ASL结论 ASL技术能探查大面积急性脑梗死的灌注情况；联合应用DWI、ASL、MRA 有助于判断IP。 |
| 英文摘要: |
| Objective To observe the value of arterial spin-labeling (ASL) combined with DWI and MRA in identifying ischemic penumbra (IP) for patients with acute stroke. Methods Forty patients with infarction within 24 h were enrolled. All patients underwent ASL, DWI and MRA examination, and were classified into ASL>DWI group (IP group), ASL≈DWI group and ASLResults There were 25 cases in ASL>DWI group (25/40, 62.50%), among them steno-occlusion were mainly graded as 0 and 1. Significant differences were found between infarct core and IP areas, as well as contralateral on ADC and rCBF (P<0.001). The distinction of IP areas between ipsilateral and contralateral cerebral tissue had no statistical significance on ADC (P=0.59), whereas had significance on rCBF (P<0.001). There were 2 cases (2/40, 5.00%) in ASL≈DWI group and 4 cases (4/40, 10.00%) in ASLn=1), 1 (n=1) and 3 (n=4). Conclusion ASL can be used to evaluate perfusion status of large area acute stroke. ASL combined with DWI and MRA can be helpful to diagnosing IP. |
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