| 张占文,陈斐妮,吕清湖,张杰,卢丹,胡平.水灌肠18F-FDG PET/CT鉴别诊断良恶性结直肠病变[J].中国医学影像技术,2013,29(12):2002~2006 |
| 水灌肠18F-FDG PET/CT鉴别诊断良恶性结直肠病变 |
| Water enema 18F-FDG PET/CT in differential diagnosis of malignant and benign lesions in rectum and sigmoid colon lesions |
| 投稿时间：2013-06-28 修订日期：2013-08-12 |
| DOI： |
| 中文关键词: 直肠 乙状结肠 灌肠 正电子发射型体层摄影术 体层摄影术,X线计算机 18F 氟脱氧葡萄糖 |
| 英文关键词:Rectum Sigmoid colon Enema Positron-emission tomography Tomography, X-ray computed Fluorodeoxyglucose F18 |
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| 中文摘要: |
| 目的 探讨水灌肠PET/CT鉴别结直肠良恶性病变的价值。方法 对常规PET/CT检查发现的45例直肠及乙状结肠局灶性或弥漫性FDG浓聚患者行水灌肠PET/CT显像，与肠镜或术后病理结果进行对照。结果 水灌肠PET/CT扫描后诊断生理性摄取准确率为100%（15/15）；诊断恶性肿瘤的敏感度为100%（18/18），特异度为92.59%（25/27），准确率为95.56%（43/45），阳性预测值为90.00%（18/20），阴性预测值为100%（27/27）。结论 水灌肠PET/CT可有效排除结直肠生理性摄取18F-FDG，准确鉴别常规PET/CT难以诊断的良恶性结直肠病变。 |
| 英文摘要: |
| Objective To assess the feasibility of water enema 18F-FDG PET/CT in differential diagnosis of malignant and benign lesions in rectum and sigmoid colon. Methods Totally 45 patients with locally hypermetabolic lesions found by 18F-fluorodexyglucose (FDG) PET/CT in rectum and sigmoid colon underwent water enema 18F-FDG PET/CT. The results of water enema 18F-FDG PET/CT were compared with colonoscopy and surgical pathological examination. Results The diagnostic accuracy of water enema 18F-FDG PET/CT for physiological 18F-FDG uptake was 100% (15/15). The diagnostic sensitivity, specificity, accuracy, positive predictive value and negative predictive value of water enema 18F-FDG PET/CT for malignant lesions was 100%(18/18), 92.59% (25/27), 95.56% (43/45), 90.00% (18/20) and 100% (27/27), respectively. Conclusion Enema water 18F-FDG PET/CT can effectively remove physiological uptake in colorectum and differ malignant and benign lesions of rectum and sigmoid colon that hard to be diagnosed with routine PET/CT. |
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