| 姚洁洁,张静雯,詹维伟,费晓春.乳腺导管内癌及其微浸润癌的临床、病理及超声特征[J].中国医学影像技术,2013,29(9):1460~1464 |
| 乳腺导管内癌及其微浸润癌的临床、病理及超声特征 |
| Clinical, histopathological and ultrasonic characteristics of breast ductal carcinoma in situ and ductal carcinoma in situ with microinvasion |
| 投稿时间：2013-04-10 修订日期：2013-06-03 |
| DOI： |
| 中文关键词: 癌,导管,乳腺 超声检查 病理学 |
| 英文关键词:Carcinoma, ductal, breast Ultrasonography Pathology |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨乳腺导管内癌(DCIS)及其微浸润癌(DCIS-MI)的临床、病理特征及超声表现。方法 回顾性分析218例DCIS患者(252个病灶)的临床、病理及超声资料。结果 252个病灶中,有172个DCIS(DCIS组)和80个DCIS-MI(DCIS-MI组),两组患者发病年龄、月经状态差异无统计学意义(P均>0.05),肿瘤大小、前哨淋巴结转移率差异有统计学意义(P均<0.05)。病理特征:DCIS-MI组粉刺型及高级别分化比例明显高于DCIS组(P<0.05);超声征象:肿瘤形状、内部回声、边缘和边界以及Adler分级两组间差异具统计学意义(P均<0.05),肿瘤后方回声、生长方位、微钙化、乳腺结构紊乱及导管扩张两组差异无统计学意义(P均>0.05)。结论 DCIS-MI较DCIS更具浸润性癌的临床特征,其部分超声征象具恶性肿瘤特征,可反映其病理特点。 |
| 英文摘要: |
| Objective To explore the clinical, pathological and ultrasonic characteristics of breast ductal carcinoma in situ (DCIS) and DCIS with microinvasion (DCIS-MI). Methods The clinical, pathological and ultrasonic data of 218 cases (252 lesions) of DCIS were retrospectively analyzed and compared. Results There were 172 lesions of DCIS (DCIS group) and 80 lesions of DCIS-MI (DCIS-MI group). There was no significant difference of age nor menopausal status between the two groups (both P>0.05), but the tumor size and sentinel lymph node metastasis rate showed statistical differences between them (both P<0.05). For pathological features, the rates of comedo type and high level differentiation nuclear in DCIS-MI group were higher than those in DCIS group (P<0.05). On ultrasonography, there were significant differences of tumor shape, internal echo, edge and boundary and Adler flow grade (all P<0.05), whereas the rear echo, growth direction, microcalcification, structural disorder and ductal dilatation showed no differences (all P>0.05) between the two groups. Conclusion DCIS-MI shows more clinical characteristics of invasive cancer than DCIS. Parts ultrasonic features of DCIS-MI more obviously tend to malignant tumor than DCIS, reflecting the pathological features of it. |
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