石喻,郭启勇,张兰,卞胜昕,于兵.门静脉血流灌注对健康志愿者肝脏MR弹性值的影响[J].中国医学影像技术,2013,29(8):1327~1330
门静脉血流灌注对健康志愿者肝脏MR弹性值的影响
Influence of portal vein perfusion on MR elastography of liver in healthy volunteers
投稿时间:2013-01-18  修订日期:2013-06-01
DOI:
中文关键词:    磁共振成像  灌注成像
英文关键词:Liver  Magnetic resonance imaging  Perfusion imaging
基金项目:国家自然科学基金面上项目(81071123、81271566)。
作者单位E-mail
石喻 中国医科大学附属盛京医院放射科, 辽宁 沈阳 110004  
郭启勇 中国医科大学附属盛京医院放射科, 辽宁 沈阳 110004 guoqy@sj-hospital.org 
张兰 中国医科大学附属盛京医院放射科, 辽宁 沈阳 110004  
卞胜昕 中国医科大学附属盛京医院放射科, 辽宁 沈阳 110004  
于兵 中国医科大学附属盛京医院放射科, 辽宁 沈阳 110004  
摘要点击次数: 2845
全文下载次数: 954
中文摘要:
      目的 探讨门静脉血流灌注量的改变对磁共振弹性成像(MRE)所测肝弹性值的影响。方法 对32名健康志愿者分别在空腹和进食标准餐后(可有效增加门静脉灌注量)定量测量门静脉灌注量及肝弹性值,并进行比较分析。结果 进食后门静脉灌注量均显著上升,平均幅度123.5%。进食前、后的平均肝弹性值分别为(2.30±0.28)kPa及(2.32±0.24)kPa,差异无统计学意义(t=-0.63,P=0.54);门静脉灌注量与肝弹性值的变化无明显相关性(r=0.15,P=0.42)。结论 正常人餐后肝脏门静脉灌注变化不会引起肝脏弹性值的变化,进食状态不影响MRE测量结果的可重复性。
英文摘要:
      Objective To observe the influence of portal vein perfusion on liver stiffness measured by MR elastography (MRE) in healthy volunteers. Methods Liver stiffness and perfusion of portal vein were measured and compared in 32 healthy volunteers before and after a standard meal which can effectively increase portal vein flow. Results Portal vein flow significantly increased at the postprandial state, and the mean increasing rate was 123.5%.The mean liver stiffness measured before and after a standard meal had no significant difference ( kPa vs kPa, t=-0.63,P=0.54). There was no significant correlation between the percentage change in stiffness and portal vein flow (r=0.15, P=0.42). Conclusion MRE can provide repeatable stiffness estimation of the liver in both fasted or fed state for healthy subjects, and the measurements are not related to portal vein flow.
查看全文  查看/发表评论  下载PDF阅读器