牛建梅,孙立群,张娟,张会萍,周雷平,曾敏,强素凤,杜联芳.超声造影定量分析鉴别诊断卵巢良恶性肿瘤[J].中国医学影像技术,2013,29(6):994~997
超声造影定量分析鉴别诊断卵巢良恶性肿瘤
Quantitative analysis of CEUS in differential diagnosis of benign and malignant ovarian tumors
投稿时间:2013-02-23  修订日期:2013-04-07
DOI:
中文关键词:  卵巢肿瘤  超声检查  造影剂  时间-强度曲线
英文关键词:Ovarian neoplasms  Ultrasonography  Contrast media  Time-intensity curve
基金项目:上海市科委医学引导类科技项目(114119a1000)。
作者单位E-mail
牛建梅 上海交通大学附属国际和平妇幼保健院, 超声科, 上海 200030  
孙立群 上海交通大学附属国际和平妇幼保健院, 超声科, 上海 200030  
张娟 上海交通大学附属第一人民医院超声科, 上海 200080  
张会萍 上海交通大学附属第一人民医院超声科, 上海 200080  
周雷平 上海交通大学附属国际和平妇幼保健院, 超声科, 上海 200030  
曾敏 上海交通大学附属国际和平妇幼保健院, 超声科, 上海 200030  
强素凤 上海交通大学附属国际和平妇幼保健院, 超声科, 上海 200030  
杜联芳 上海交通大学附属第一人民医院超声科, 上海 200080 du_lf@163.com 
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中文摘要:
      目的 探讨CEUS在鉴别诊断卵巢良恶性肿瘤中的应用价值。 方法 纳入因卵巢肿瘤接受手术的患者48例,共51个肿块,于术前1周内行经腹CEUS检查,动态观察肿瘤的造影增强模式,绘制肿瘤ROI时间-强度曲线并获得峰值强度(Imax)、上升时间(RT)、达峰时间(TTP)、平均渡越时间(mTT)及曲线下面积(AUC);比较良恶性肿瘤间各参数差异。 结果 51个肿块中,良性肿瘤24个,恶性肿瘤27个;CEUS中良性肿瘤呈均匀增强,恶性肿瘤呈不均匀增强;恶性肿瘤造影剂Imax、AUC和mTT均大于良性肿瘤(P均<0.05), 而RT和TTP二者间差异无统计学意义(P均>0.05)。 结论 CEUS可准确评价肿瘤内血流灌注特点,在鉴别诊断卵巢良恶性肿瘤中有重要应用价值。
英文摘要:
      Objective To investigate the value of CEUS in differential diagnosis of benign and malignant ovarian tumors. Methods Totally 48 cases (51 masses) receiving surgery due to ovarian neoplasms were enrolled. Transabdominal CEUS was performed within 1 week before surgery. The enhanced pattern of the tumor was dynamically observed, and the maximal intensity (Imax), rising time (RT), time to peak (TTP), mean transit time (mTT) and area under the curve (AUC) of contrast agent obtained from time-intensity curve were compared between benign and malignant tumors. Results There were 24 benign tumors and 27 malignant tumors. In CEUS, benign tumors showed homogenous enhancement, while malignant tumors showed heterogeneous enhancement. Imax, AUC and mTT of contrast agent of malignant tumors were all higher than those of benign tumor (all P<0.05), but there was no significant difference of RT nor TTP between benign and malignant tumors (both P>0.05). Conclusion CEUS can accurately assess the perfusion characteristics of tumors, therefore having great application value in differential diagnosis of benign and malignant ovarian tumors.
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