| 姜双全,姜丽丽,王影,苏雁欣,田家玮.常规超声及弹性成像诊断甲状腺微小癌的应用价值[J].中国医学影像技术,2013,29(4):528~531 |
| 常规超声及弹性成像诊断甲状腺微小癌的应用价值 |
| Evaluation on the effect of conventional ultrasonography and elastography in diagnosis of thyroid microcarcinoma |
| 投稿时间：2012-09-08 修订日期：2013-02-10 |
| DOI： |
| 中文关键词: 超声检查 弹性成像技术 甲状腺结节 甲状腺肿瘤 |
| 英文关键词:Ultrasonography Elasticity imaging techniques Thyroid nodule Thyroid neoplasms |
| 基金项目: |
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| 摘要点击次数: 2142 |
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| 中文摘要: |
| 目的 探讨常规超声、弹性成像及二者联合应用诊断甲状腺微小癌(TMC)的价值。方法 回顾性分析140例(166枚结节)甲状腺结节患者的完整超声检查资料(包括弹性成像),观察甲状腺结节声像图,并进行评分;以病理结果为金标准,分别绘制应用常规超声(Ⅰ组)、弹性成像(Ⅱ组)及常规超声联合弹性成像(Ⅲ组)诊断甲状腺结节良恶性的ROC曲线,比较ROC曲线下面积(AUC),确定最佳诊断界点。 结果 Ⅰ组、Ⅱ组、Ⅲ组AUC分别为0.901、0.879及0.956。Ⅰ组与Ⅱ组间差异无统计学意义(Z=0.593,P=0.553);Ⅰ组与Ⅲ组间差异有统计学意义(Z=3.936,P=0.0001);Ⅱ组与Ⅲ组间差异有统计学意义(Z=2.651,P=0.008)。Ⅰ、Ⅱ、Ⅲ组最佳诊断界点分别为5分、3分、7分,其敏感度与特异度分别为84.9%与86.0%、87.7%与84.9%、95.6%与82.2%。 结论 常规超声及弹性成像诊断TMC均有较高准确性,二者联合应用可进一步提高超声诊断效能, 降低漏诊率。 |
| 英文摘要: |
| Objective To explore the value of conventional ultrasonography, elastography and the combination of the two methods for diagnosis of thyroid microcarcinoma (TMC). Methods Integrated sonographic data (including elastography) of 140 patients (166 nodules) with thyroid nodule were analyzed retrospectively, and sonogram of these cases were observed and scored carefully. All the lesions were confirmed by pathology. ROC curves were drawn to distinguish benign and malignant lesions according to the features of conventional ultrasonography (group Ⅰ), elastography (group Ⅱ) and the combination of them (group Ⅲ), and the area under the curve (AUC) of the three groups were compared, the cut-off values were defined. Results The AUC of group Ⅰ, Ⅱ and Ⅲ was 0.901, 0.879 and 0.956, respectively. The difference between group Ⅰand Ⅱ was not statistically significant (Z=0.593, P=0.553), while between group Ⅰand Ⅲ, was statistically significant (Z=3.936, P=0.0001), so as between group Ⅱ and Ⅲ (Z=2.651, P=0.008). The cut-off value of group Ⅰ, Ⅱ and Ⅲ was 5, 3 and 7, respectively, and the sensitivity and specificity was 84.9% and 86.0%, 87.7% and 84.9%, 95.6% and 82.2%, respectively. Conclusion Both conventional US and elastography show considerable accuracy for diagnosis of TMC. Combination of them can elevate diagnosis efficacy of ultrasound, improve the sensitivity and decrease miss diagnosis. |
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