| 陈越峰,丛淑珍,甘科红,周立峰,安秀艳.实时超声弹性定量诊断酒精性肝纤维化[J].中国医学影像技术,2013,29(3):429~432 |
| 实时超声弹性定量诊断酒精性肝纤维化 |
| Real-time ultrasonic elasticity quantitative diagnosis of alcoholic liver fibrosis |
| 投稿时间：2012-09-20 修订日期：2013-01-05 |
| DOI： |
| 中文关键词: 弹性成像技术 定量分析 肝硬化 |
| 英文关键词:Elasticity imaging technique Quantitative analysis Liver cirrhosis |
| 基金项目:广东省科技计划项目(粤科规划字2011177号)、广东省医学科研基金(A2012037)。 |
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| 中文摘要: |
| 目的: 探讨实时超声弹性定量诊断酒精性肝纤维化的可行性,筛选敏感参数,并评价其诊断价值。方法: 回顾分析85例长期饮酒患者的实时超声弹性定量图及定量参数,并与肝纤维化病理分期进行相关分析。结果: 应变均值(MEAN)、蓝色区域百分比(AREA)与肝纤维化病理分期高度相关(r=-0.83、0.85,P<0.01)。随着肝纤维化分期增加,MEAN逐渐减少,AREA逐渐增加,各分期间差异有统计学意义(P<0.05)。MEAN和AREA在各分期的ROC曲线下面积均≥0.90。结论: 实时超声弹性可定量诊断酒精性肝纤维化;AREA、MEAN是评估肝纤维化分期的敏感的定量参数。 |
| 英文摘要: |
| Objective: To explore the feasibility of real-time ultrasonic elasticity quantitative for diagnosing alcoholic liver fibrosis, and to screen sensitive parameters through assessing the diagnostic value of them. Methods: Eighty-five patients with long-term drinking history who underwent real-time ultrasonic elasticity quantitative examination were retrospectively analyzed, and the results of liver fibrosis staging according to quantitative parameters were compared with those of pathology. Results: MEAN and AREA had significant correlation with pathological staging of liver fibrosis (r=-0.83, 0.85, P<0.01). Along with the staging increased, MEAN gradually reduced, while AREA increased, and all the differences had statistical significance (all P<0.05). The areas under ROC curves of MEAN and ARER were all ≥0.90. Conclusion: Real-time ultrasonic elasticity can quantitatively diagnose alcoholic liver fibrosis. AREA and MEAN can assess the staging of liver fibrosis sensitively. |
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