| 齐燕,欧陕兴,钱民,彭光明,刘波,刘玉品.DECT首过心肌灌注成像的临床应用[J].中国医学影像技术,2013,29(3):375~379 |
| DECT首过心肌灌注成像的临床应用 |
| Clinical application of dual-energy CT first-pass myocardial perfusion imaging |
| 投稿时间：2012-07-22 修订日期：2012-11-30 |
| DOI： |
| 中文关键词: 体层摄影术,X线计算机 灌注成像 早期灌注缺损 |
| 英文关键词:Tomography, X-ray computed Perfusion imaging Early perfusion defect |
| 基金项目: |
|
| 摘要点击次数: 3351 |
| 全文下载次数: 1118 |
| 中文摘要: |
| 目的: 探讨双源CT(DECT)心肌灌注成像的临床应用价值。方法: 选取59例接受DECT心肌灌注成像及SPECT负荷心肌显像者,根据检查结果分为A组(对照组,20例)和B组(缺血性心脏病组,39例),测量A组各心肌节段以及B组灌注缺损区、缺损周边及缺损对侧心肌CT灌注值(VNC及Overlay值)。比较DECT与SPECT检出早期心肌灌注缺损(EPD)的差异,分析冠状动脉狭窄程度对两种检查方法一致性的影响。结果: A组心尖部、中间部及基底部VNC、Overlay值的差异无统计学意义(P均>0.05)。B组中DECT检出92处EPD,其中53处经SPECT证实,二者检查结果的差异无统计学意义(χ2=3.403,P=0.065),呈中等相关(r=0.533,P<0.01)。供血冠脉轻度狭窄时两种检查方法检出EDP的差异有统计学意义(χ2=11.396,P<0.01),而中度及重度狭窄时两种检查方法检出EDP的差异无统计学意义(P均>0.05)。结论: DECT首过心肌灌注成像能准确评估正常心肌及缺血心肌的灌注情况,与SPECT检查结果具有相关性,且更易检出早期、轻度心肌缺血。 |
| 英文摘要: |
| Objective: To explore the clinical application of dual-energy CT (DECT) myocardial perfusion images. Methods: Totally 59 patients underwent DECT perfusion and SPECT stress test, and were divided into group A (control group, n=20) and group B (ischemic heart disease group, n=39) according to the results. DECT myocardial perfusion was evaluated for the attenuation value (VNC and Overlay) of all segments in group A and the early perfusion defect (EPD), peripheral and opposite segment in group B. EPD was detected by DECT and compared to the results of SPECT. The relationship between extent of coronary artery stenosis and the consistency of results between DECT and SPECT were analyzed. Results: In group A, there was no significant difference of VNC nor Overlay among the apical, middle and basal segments by DECT (P>0.05). In group B, EPD was detected in 92 segments by DECT, in which 53 segments were confirmed by SPECT. The results of DECT and SPECT had no significant difference (χ2=3.403, P=0.065), and had a moderate correlation (r=0.533, P<0.01). When mild stenosis of the coronary artery was found, significant differences of EDP detection existed between DECT and SPECT (χ2=11.396, P<0.01), whereas no significant difference was found between DECT and SPECT when moderate and severe stenosis of coronary artery occurred (both P>0.05). Conclusion: The characterization of myocadial perfusion in healthy people and patients with myocardial ischemia can be obtained by first-pass myocardial perfusion imaging with those of DECT. The results of DECT have correlation with SPECT. DECT is more sensitive in detecting early mild myocardial ischemia than SPECT. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
