| 陈贵兵,林金海,黄劲雄,何小江,俞浩,许威毅,肖小兰,王璘.99mTc-Octreotide显像与高频超声在甲状腺实性冷结节定性诊断中的比较[J].中国医学影像技术,2013,29(3):354~357 |
| 99mTc-Octreotide显像与高频超声在甲状腺实性冷结节定性诊断中的比较 |
| Comparison on 99mTc-Octreotide scintigraphy and high-frequency ultrasonography in qualitative diagnosis of thyroid solid and cold nodule |
| 投稿时间：2012-04-09 修订日期：2013-01-10 |
| DOI： |
| 中文关键词: 甲状腺结节 放射性核素显像 超声检查 |
| 英文关键词:Thyroid nodule Radionuclide imaging Ultrasonography |
| 基金项目:2007年厦门市卫生局青年创新科研项目(WQK0703)。 |
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| 中文摘要: |
| 目的: 比较99mTc-Octreotide显像与高频超声在甲状腺实性冷结节定性诊断中的价值。方法: 对82例高频超声检查为实性结节、甲状腺静态显像呈"冷结节"的患者于超声检查3天内行99mTc-Octreotide显像,并将结果与术后病理结果进行对照。结果: 82例患者中,恶性结节31例,良性结节51例。99mTc-Octreotide显像、高频超声及二者联合显像诊断恶性结节的灵敏度、特异度、阳性预测值、阴性预测值和准确率分别为70.97%(22/31)、96.08%(49/51)、91.67%(22/24)、84.48%(49/58)、86.59%(71/82),77.42%(24/31)、84.31%(43/51)、75.00%(24/32)、86.00%(43/50)、81.71%(67/82)及87.10%(27/31)、98.04%(50/51)、96.43%(27/28)、92.59%(50/54)、93.90%(77/82)。结论: 99mTc-Octreotide显像与高频超声均对定性诊断甲状腺实性"冷结节" 具有良好效能,而99mTc-Octreotide显像特异度较高。 |
| 英文摘要: |
| Objective: To compare the value of 99mTc-Octreotide scintigraphy and high-frequency ultrasonography in qualitative diagnosis of thyroid solid and cold nodule. Methods: Eighty-two patients with solid nodule confirmed by high-frequency ultrasonography and cold nodule confirmed by thyroid scan were enrolled. All patients underwent 99mTc-Octreotide scintigraphy within 3 days, and the results were compared with those of post-surgery pathology. Results: Among 82 patients, there were 31 malignant and 51 benign thyroid nodules. The sensitivity, specificity, positive predicting value, negative predicting value and accuracy rate of 99mTc-Octreotide scintigraphy, high-frequency ultrasonography and combined imaging in detecting thyroid malignant nodules were 70.97% (22/31), 96.08% (49/51), 91.67% (22/24), 84.48% (49/58), 86.59% (71/82); 77.42% (24/31), 84.31% (43/51), 75.00% (24/32), 86.00% (43/50), 81.71% (67/82) and 87.10% (27/31), 98.04% (50/51), 96.43% (27/28), 92.59% (50/54), 93.90% (77/82). Conclusion: 99mTc-Octreotide scintigraphy and high-frequency ultrasonography may both offer good efficacy for qualitative diagnosis of thyroid solid and cold nodule, while 99mTc-Octreotide scintigraphy has higher specificity. |
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