| 马春燕,赵红,刘爽,张妍,赵斓婷,唐力,于波,杨军.超声心动图预测心脏再同步化治疗超反应的价值[J].中国医学影像技术,2013,29(1):42~45 |
| 超声心动图预测心脏再同步化治疗超反应的价值 |
| Value of echocardiography in prognosticating super-responders to cardiac resynchronization therapy |
| 投稿时间：2012-08-17 修订日期：2012-10-20 |
| DOI： |
| 中文关键词: 超声心动描记术 再同步化治疗 超反应 |
| 英文关键词:Echocardiography Cardiac resynchronization therapy Super-responder |
| 基金项目:辽宁省自然科学基金(20102280)。 |
|
| 摘要点击次数: 2438 |
| 全文下载次数: 1284 |
| 中文摘要: |
| 目的 探讨超声心动图预测心脏再同步化治疗(CRT)超反应的价值。方法 对78例接受CRT术的慢性心力衰竭患者,分别于术前7天和术后1年行超声检查,测量左心室舒张末径(LVEDD)和射血分数(LVEF)、二尖瓣血流舒张早期(E)和舒张晚期速度(A),计算E/A和二尖瓣反流面积(MRA);以二维斑点追踪技术检测左心室收缩同步性(SI)。将CRT术后LVEF增加<5%定义为无反应组(CRT-NR),LVEF增加≥5%但LVEF<50%为CRT有反应组(CRT-R),LVEF≥50%为CRT超反应组(CRT-SR)。对3组间各参数进行统计学比较。结果 术后12例为CRT-SR组(12/78,15.38%),其中扩张型心肌病(DCM)所占比例、左束支传导阻滞(LBBB)所占比例及其SI均大于CRT-NR组(19例,19/78,24.36%),MRA、E/A则小于CRT-NR组。CRT-SR组和CRT-R组(47例,47/78,60.26%)间DCM所占比例、LBBB所占比例、MRA和E/A差异有统计学意义。术前DCM所占比例、LBBB所占比例、MRA和E/A均与CRT超反应相关(r=0.51,0.40,－0.38,－0.32,P均<0.01)。结论 CRT术前DCM合并LBBB、MRA较小和非限制型舒张功能减低患者术后更易出现超反应。 |
| 英文摘要: |
| Objective To investigate the role of echocardiography in prognosticating super-responders (SR) to cardiac resynchronization therapy (CRT). Methods Seventy-eight heart failure patients underwent echocardiography examination 7 days before and 1 year after CRT. Left ventricular end-diastolic dimension (LVEDD), ejection fraction (LVEF), mitral regurgitation area (MRA), and the ratio of mitral inflow early-diastolic to late-diastolic velocity (E/A) were measured. Meanwhile, LV synchrony index (SI) was detected using two-dimensional speckle tracking imaging. Patients with LVEF increase <5% were classified as non-responders (CRT-NR group), LVEF increase ≥5% and LVEF <50% as responders (CRT-R group), and those LVEF ≥50% were considered as super-responders (CRT-SR group) 1 year after CRT. Parameters among three groups were compared statistically. Results Twelve patients (12/78, 15.38%) were classified as CRT-SR. Compared with CRT-NR group (19/78, 24.36%), there were more left bundle branch block (LBBB) and dilated cardiomyopathy (DCM) in CRT-SR group, longer SI and smaller MRA and E/A. The ratio of DCM, ratio of LBBB, MRA and E/A were statistical different between CRT-SR group and CRT-R group (47/78, 60.26%). Before CRT, the ratio of DCM and LBBB, MRA and E/A were correlated with super-responders (r=0.51, 0.40, －0.38, －0.32, all P<0.01). Conclusion DCM patients with LBBB, smaller MRA and non-restrictive diastolic model tend to become super-responders after CRT. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
