| 王颖,李亚明,尹雅芙,李娜.18F-FDG PET/CT对检出恶性腹腔积液患者原发癌灶的临床价值[J].中国医学影像技术,2012,28(12):2193~2196 |
| 18F-FDG PET/CT对检出恶性腹腔积液患者原发癌灶的临床价值 |
| Clinical value of 18F-FDG PET/CT in detection of original disease of patients with malignant ascites |
| 投稿时间：2012-03-29 修订日期：2012-04-16 |
| DOI： |
| 中文关键词: 肿瘤 腹腔积液 正电子发射型体层摄影术 体层摄影术,X线计算机 18F 氟脱氧葡萄糖 |
| 英文关键词:Neoplasms Ascites Positron-emission tomography Tomography, X-ray computed Fluorodeoxyglucose F18 |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨18F-FDG PET/CT显像对检出恶性腹腔积液患者原发癌灶的临床价值。方法 回顾性分析既往以腹腔积液为首发症状、在腹腔积液中发现肿瘤细胞并最终检出原发癌灶的患者51例,其中胃癌14例,肠癌7例(乙状结肠癌1例,降结肠癌1例,升结肠癌3例,直肠癌2例),卵巢癌22例,胰腺癌6例,肝癌2例,均接受体部18F-FDG PET/CT扫描,并经进一步检查或3~13个月随访证实;分别统计PET/CT及单独CT查找原发病灶的诊断价值。结果 51例中,PET/CT检查发现原发灶40例,其中胃癌10例,肠癌4例(乙状结肠癌1例,升结肠癌2例,直肠癌1例),卵巢癌19例,胰腺癌5例,肝癌2例,检出率为78.43%(40/51);11例PET/CT检查未发现原发灶,5例仅为腹膜增厚、代谢增高,3例仅为大网膜增厚、无代谢异常,3例仅提示腹腔积液。CT提示原发病灶31例,其中胃癌6例,肠癌3例,卵巢癌18例,胰腺癌3例,肝癌1例,检出率为60.78%(31/51),占PET/CT发现原发灶的77.50%(31/40)。结论 对于在不明原因腹腔积液中发现肿瘤细胞者,PET/CT查找其原发病灶具有较高临床价值。 |
| 英文摘要: |
| Objective To investigate the clinical value of 18F-FDG PET/CT in detection of the original disease of patients with malignant ascites. Methods A total of 51 patients whose primary symptom were ascites in which tumor cells had been found were included, including 14 cases of gastric cancer, 7 cases of intestinal tract cancer (1 sigmoid colon cancer, 1 descending colon cancer, 3 ascending colon cancer and 2 rectal cancer), 22 cases of ovarian cancer, 6 cases of pancreatic cancer and 2 cases of liver cancer. All patients underwent whole body PET/CT scan, and the diagnosis was confirmed by series imaging examination, gastroscopy and enteroscopy, etc. or clinical following-up of 3-13 months. The diagnostic value of PET/CT and CT in detection of the original disease was calculated, respectively. Results Of 51 patients, original disease of 40 patients were confirmed by PET/CT, including 10 cases of gastric cancer, 4 of intestinal tract cancer (1 sigmoid colon cancer, 2 ascending colon cancer and 1 rectal cancer), 19 of ovarian cancer, 5 of pancreatic cancer and 2 of liver cancer, the detection rate was 78.43% (40/51). PET/CT failed to detect the original disease of 11 cases, but found thickening and high metabolism of peritoneum in 5 cases, thickening and normal metabolism of peritoneum in 3 cases, while appearances of ascites in 3 cases. The original disease of 31 patients were confirmed by CT alone, including 6 cases of gastric cancer, 3 of intestinal tract cancer, 18 of ovarian cancer, 3 of pancreatic cancer and 1 case of liver cancer, and the detection rate was 60.78% (31/51), lower than that of PET/CT. Conclusion PET/CT is an accurate technique in detection of the original disease of patients with malignant ascites. |
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