| 周春泽,吕维富,张行明,肖景坤,张正峰,鲁东,王伟昱,侯昌龙.经皮经肝选择性门静脉栓塞技术及其安全性评价[J].中国医学影像技术,2012,28(11):2028~2032 |
| 经皮经肝选择性门静脉栓塞技术及其安全性评价 |
| Percutaneous transhepatic selective portal vein embolization: Technique and security |
| 投稿时间：2012-06-26 修订日期：2012-08-27 |
| DOI： |
| 中文关键词: 肝肿瘤 门静脉 化学栓塞,治疗性 安全性 |
| 英文关键词:Liver neoplasms Portal vein Chemoembolization, therapeutic Safety |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨经皮经肝选择性门静脉栓塞术(SPVE)的技术要点和安全性。 方法 对41例肝脏肿瘤患者(包括原发性肝癌13例,转移性肝癌28例)行SPVE,对其中32例同期行TACE术(SPVE+TACE组),9例未行或未同期行TACE术(单纯SPVE组)。术后回顾性分析SPVE的技术要点、并发症及临床安全性。 结果 对41例均成功完成SPVE术,成功率100％;术后第3天患者ALT、AST、TB较术前升高,SPVE+TACE组升高更为明显,至术后第7天均明显下降。5例出现SPVE相关并发症,包括2例异位门静脉栓塞、1例暂时性肝功能衰竭、1例肝包膜下出血和1例肝内门静脉-静脉瘘。 结论 SPVE作为肝脏外科手术和TACE术的重要辅助技术是可行的,但术后相关并发症应引起足够重视。 |
| 英文摘要: |
| Objective To discuss the main technical methods of percutaneous transhepatic selective portal vein embolization (SPVE), and to assess its security. Methods Forty-one patients (13 with primary liver carcinoma and 28 with metastatic liver cancer) underwent SPVE, 32 of which simultaneously underwent TACE (SPVE+TACE group), while 9 of which did not undergo TACE within 1 week of SPVE (single SPVE group). The technology of SPVE, procedure-related complications and its clinical security were retrospectively analyzed. Results SPVE was successfully performed in all 41 patients, and the success rate was 100%. On the 3rd day after treatment, alanine aminotransferase (ALT), aspartate aminotransferase (AST) and total bilirubin (TB) increased, in SPVE+TACE group more obviously than in single SPVE group. However, on the 7th day after treatment, ALT, AST and TB decreased significantly. Complications caused by SPVE occurred in 5 patients, including ectopic portal embolization in 2 patients, transient liver failure, liver capsule bleeding, and portal vein-hepatic vein fistula in 1 patient, respectively. Conclusion SPVE is an important aided technology for liver surgery and TACE. However, sufficient attention should be paid to the relevant complications caused by the operation. |
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